A6QLI5
Gene name |
MAGED4 |
Protein name |
Melanoma-associated antigen D4 |
Names |
MAGE-D4 antigen |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:100125231 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6QLI5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6QLI5-F1 | Predicted | AlphaFoldDB |
No variants for A6QLI5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6QLI5 | |||||
No associated diseases with A6QLI5
1 regional properties for A6QLI5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | MAGE homology domain | 414 - 612 | IPR002190 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of transcription by RNA polymerase II | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q96JG8 | MAGED4B | Melanoma-associated antigen D4 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEGSYRKES | EGYNVEDMDE | GSDEVGEEDM | VEGNDYEEFG | AFGGYGALTS | FDIRILRAFG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SLGPGFRILA | NEPWELENPV | LARTLLEAFR | MDPETLANET | AARAANVARA | AASNQAARAA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ATAARATYNQ | VVTNHHPVAT | HQASGGDTQP | MTSAAQAPAA | TPETSVASPH | SSRMLVNSEM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AAPGAPARSP | QPQTSSQAQE | AAAEGPSTAC | AFPQASRASE | MDATRPKTAF | LGQNDAFDFS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QPAGVSGMAF | PRPKRPAPAQ | EAATEGPSVA | SRGTQAASAG | EGAATRPKTT | KSGKALAKTR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| WVEPQNVVAA | AAAKAKMATS | IPEPESAAAT | SQQSAEPWAR | MGGKRTKKSK | HLDDEYESGE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EEREPPAVPP | TWRASQPLLT | TARPQVAPRP | SMALRSQVPS | RHVLCLPPRN | VTLLQERANK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LVKYLMIKDY | KKIPIKRSDM | LKDVIREYDE | HFPEIIERAT | YTLEKKFGIH | LKEIDKEEHL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| YILVCTRDSS | ARLLGKTKDT | PRLSLLLVIL | GVIFMNGNRA | SEAVLWEALR | KMGLRPGVRH |
| 550 | 560 | 570 | 580 | 590 | 600 |
| PFLGDLRKLI | TEDFVKQKYL | EYKKVPNSSP | PEYEFLWGLR | ACHETSKMRV | LRFIAQYQNR |
| 610 | 620 | 630 | 640 | 650 | 660 |
| DPREWRAHFL | EAVDDAFKTM | DVDMAEEHAR | AQMRAQMNIG | EEALIGRWSW | DDIQVELLTW |
| 670 | 680 | 690 | 700 | 710 | 720 |
| DEDGDFGDAW | SRIPFAFWAR | YHQYILNSNR | PNRRGTWRAG | VSSGTNGAAS | ASMLDGPSTS |
| 730 | |||||
| STIRTRNAAR | TSASFFSWIQ |