Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A3KPW7

Entry ID Method Resolution Chain Position Source
AF-A3KPW7-F1 Predicted AlphaFoldDB

No variants for A3KPW7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A3KPW7

No associated diseases with A3KPW7

4 regional properties for A3KPW7

Type Name Position InterPro Accession
repeat Protein prenyltransferase, alpha subunit 118 - 152 IPR002088-1
repeat Protein prenyltransferase, alpha subunit 177 - 211 IPR002088-2
repeat Protein prenyltransferase, alpha subunit 217 - 247 IPR002088-3
repeat Protein prenyltransferase, alpha subunit 289 - 317 IPR002088-4

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
protein prenyltransferase activity Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein.

1 GO annotations of biological process

Name Definition
protein prenylation The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q7Z6K3 PTAR1 Protein prenyltransferase alpha subunit repeat-containing protein 1 Homo sapiens (Human) PR
10 20 30 40 50 60
MAESEEEVDV LVQRVVKDIT NAFKRNPNID EIGLIPCPEA RYNRSPIVLV ENKLGVESWC
70 80 90 100 110 120
VKFLLPYVHN KLLLYRQRKQ WLDREALVDI TSTLLLLNPD FTTAWNVRKE LLQCGVLNPE
130 140 150 160 170 180
KDLYLGKLAL SKHPKSPETW IHRRWVLQRL QKECSPSGQE LKDSAESRRQ CERLQRALQE
190 200 210 220 230 240
EMRVCAEAAG RYPSNYNAWS HRIWVLQNMA KGNLKVLHDE LSSTRLWVSM HVSDHSGFHY
250 260 270 280 290 300
RQHLLKALAK ELSPAAEKDV HTSQQPNGEN TATASDDNHH KDVMPRLFHE EIQLCTDLIE
310 320 330 340 350 360
SYPGHETLWC HRRHVFYLWH QWRREHMQGA GSQSPALTHT DVLLSKELCD NNSISQAMDI
370 380 390 400 410 420
DCVLDGSKHG SYTQDTKRLK RGPLLLQPGF PSEHTFISRI LTGCRNPEQS RFAIAYRKWL
DSVIGQ