A3KGT9
Gene name |
agpat9l (si:ch211-155m12.4) |
Protein name |
Glycerol-3-phosphate acyltransferase 3-like |
Names |
1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9-like, 1-AGP acyltransferase 9-like, 1-AGPAT 9-like, Lysophosphatidic acid acyltransferase theta-like, LPAAT-theta-like |
Species |
Danio rerio (Zebrafish) (Brachydanio rerio) |
KEGG Pathway |
dre:567414 |
EC number |
2.3.1.15: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A3KGT9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A3KGT9-F1 | Predicted | AlphaFoldDB |
No variants for A3KGT9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A3KGT9 | |||||
No associated diseases with A3KGT9
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.15 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| 1-acylglycerol-3-phosphate O-acyltransferase activity | Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate. |
| glycerol-3-phosphate O-acyltransferase activity | Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate. |
| sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity | Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = coenzyme A + 1-C16:0-alpha,omega-dicarboxyl-2-lysophosphatidate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| CDP-diacylglycerol biosynthetic process | The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. |
| triglyceride biosynthetic process | The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol. |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A3FPG8 | GPAT4 | Glycerol-3-phosphate acyltransferase 4 | Bos taurus (Bovine) | PR |
| Q5ZLL8 | GPAT3 | Glycerol-3-phosphate acyltransferase 3 | Gallus gallus (Chicken) | PR |
| Q8NF37 | LPCAT1 | Lysophosphatidylcholine acyltransferase 1 | Homo sapiens (Human) | PR |
| Q86UL3 | GPAT4 | Glycerol-3-phosphate acyltransferase 4 | Homo sapiens (Human) | PR |
| Q8K2C8 | Gpat4 | Glycerol-3-phosphate acyltransferase 4 | Mus musculus (Mouse) | PR |
| Q8C0N2 | Gpat3 | Glycerol-3-phosphate acyltransferase 3 | Mus musculus (Mouse) | PR |
| Q8S8S2 | LPEAT2 | Lysophospholipid acyltransferase LPEAT2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q6PBN5 | aup1 | Lipid droplet-regulating VLDL assembly factor AUP1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q1LWG4 | lpcat1 | Lysophosphatidylcholine acyltransferase 1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEGYWAVLFP | VLKVWFSCVI | VLIMLPAMFG | ISLGITETYM | KLLIKTLEWA | THRIQRASRA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EEILKESASN | GLIQRDNSSL | EQEIEELRRN | RPKSADRGDF | TLSDVLYFSR | KGFESIVEDD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VTQRFTSEEL | VSWNLLTRTN | NNFQYISLRL | TVLWVVGVVV | RYCILLPLRI | TLTTIGLTWL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VIGTTTVGFL | PNCRVKNWLS | ELVHLMCYRI | CARGLSATIH | FHNKQNRPKK | GGICVANHTS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PIDVVILAND | GCYAMVGQVH | GGLMGVLQRA | MERSCPHIWF | ERSEMRDRHL | VTQRLKDHVN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AKTKLPILIF | PEGTCINNTS | VMMFKKGSFE | IGGTIYPVAI | KYDPQFGDAF | WNSSKYSIMS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YLLRMMTSWA | IVCNVWYLPP | MTHEEGEDAV | QFANRVKSTI | AQQGGLVDLA | WDGGLKRAKV |
| 430 | 440 | ||||
| KDSFKEQQQK | KYSHMVVGED | SSD |