T2G899

PR
Gene name
aprB
Protein name
Adenylylsulfate reductase subunit beta
Names
AdoPSO(4) reductase subunit B, Adenosine 5'-phosphosulfate reductase subunit beta, APSR subunit B
Species
Megalodesulfovibrio gigas (strain ATCC 19364 / DSM 1382 / NCIMB 9332 / VKM B-1759) (Desulfovibrio gigas)
KEGG Pathway
dgg:DGI_0458
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

81-167 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for T2G899

Entry ID Method Resolution Chain Position Source
3GYX X-ray 320 A B/D/F/H/J/L 2-167 PDB
AF-T2G899-F1 Predicted AlphaFoldDB

No variants for T2G899

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for T2G899

No associated diseases with T2G899

3 regional properties for T2G899

Type Name Position InterPro Accession
domain 4Fe-4S ferredoxin-type, iron-sulphur binding domain 1 - 67 IPR017896
conserved_site 4Fe-4S ferredoxin, iron-sulphur binding, conserved site 47 - 58 IPR017900
domain Adenylylsulphate reductase, beta subunit, C-terminal 65 - 134 IPR022738

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
metal ion binding Binding to a metal ion.
protein heterodimerization activity Binding to a nonidentical protein to form a heterodimer.

2 GO annotations of biological process

Name Definition
dissimilatory sulfate reduction The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide.
protein heterotetramerization The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPTFVDPSKC DGCKGGEKTA CMYICPNDLM ILDPEEMKAF NQEPEACWEC YSCIKICPQG
70 80 90 100 110 120
AITARPYADF APMGGTCIPL RGSEDIMWTI KFRNGSVKRF KFPIRTTPEG SIKPFEGKPE
130 140 150 160
AGDLENELLF TETALTVPQV ALGQKAQIAD AETSQCWFDL PCEGGNR