S4UX02

PR
Gene name
CYP76AH1
Protein name
Ferruginol synthase
Names
Cytochrome P450 76AH1
Species
Salvia miltiorrhiza (Chinese sage)
KEGG Pathway
ag:AGN04215
EC number
1.14.14.175: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

102-175 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

4 structures for S4UX02

Entry ID Method Resolution Chain Position Source
5YLW X-ray 170 A A 1-495 PDB
5YM3 X-ray 260 A A 1-495 PDB
7CB9 X-ray 190 A A 1-495 PDB
AF-S4UX02-F1 Predicted AlphaFoldDB

No variants for S4UX02

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for S4UX02

No associated diseases with S4UX02

1 regional properties for S4UX02

Type Name Position InterPro Accession
conserved_site Cytochrome P450, conserved site 430 - 439 IPR017972

Functions

Description
EC Number 1.14.14.175 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Subcellular Localization
  • Endoplasmic reticulum membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

3 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.

1 GO annotations of biological process

Name Definition
diterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDSFPLLAAL FFIAATITFL SFRRRRNLPP GPFPYPIVGN MLQLGANPHQ VFAKLSKRYG
70 80 90 100 110 120
PLMSIHLGSL YTVIVSSPEM AKEILHRHGQ VFSGRTIAQA VHACDHDKIS MGFLPVASEW
130 140 150 160 170 180
RDMRKICKEQ MFSNQSMEAS QGLRRQKLQQ LLDHVQKCSD SGRAVDIREA AFITTLNLMS
190 200 210 220 230 240
ATLFSSQATE FDSKATMEFK EIIEGVATIV GVPNFADYFP ILRPFDPQGV KRRADVFFGK
250 260 270 280 290 300
LLAKIEGYLN ERLESKRANP NAPKKDDFLE IVVDIIQANE FKLKTHHFTH LMLDLFVGGS
310 320 330 340 350 360
DTNTTSIEWA MSELVMNPDK MARLKAELKS VAGDEKIVDE SAMPKLPYLQ AVIKEVMRIH
370 380 390 400 410 420
PPGPLLLPRK AESDQEVNGY LIPKGTQILI NAYAIGRDPS IWTDPETFDP ERFLDNKIDF
430 440 450 460 470 480
KGQDYELLPF GSGRRVCPGM PLATRILHMA TATLVHNFDW KLEDDSTAAA DHAGELFGVA
490
VRRAVPLRII PIVKS