Q9ZN40
Gene name |
lpxE |
Protein name |
Lipid A 1-phosphatase |
Names |
|
Species |
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99) |
KEGG Pathway |
hpj:jhp_0019 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9ZN40
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9ZN40-F1 | Predicted | AlphaFoldDB |
No variants for Q9ZN40
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9ZN40 | |||||
No associated diseases with Q9ZN40
1 regional properties for Q9ZN40
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Calcineurin-like phosphoesterase domain, lpxH-type | 6 - 216 | IPR024654 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| phosphatase activity | Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid A biosynthetic process | The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common. |
| lipopolysaccharide biosynthetic process | The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. |
| mitigation of host defenses by symbiont | A process by which an organism avoids or tolerates the effects of its host organism's defense response. The host defense response is mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
| response to antibiotic | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKKFLFKQKF | CESLPKSFSK | TLLALSLGLI | LLGVFIPFPK | VPKHQSVPLA | LHFTEHYARF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IPTILSVAIP | LIQRDAVGLF | QVANASIATT | FLTHATKRAL | NHVTINDQRL | GERPYGGNFN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MPSGHSSMVG | LAVAFLMRRY | SVKKYLWLLP | LIPLTMLARI | YLDMHTIGAV | LAGLGTGMLC |
| 190 | |||||
| VGLFTSPKNL | N |