Q9ZM10

PR
Gene name
ppk
Protein name
Polyphosphate kinase
Names
ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase
Species
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
KEGG Pathway
hpj:jhp_0413
EC number
2.7.4.1: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

622-675 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9ZM10

Entry ID Method Resolution Chain Position Source
AF-Q9ZM10-F1 Predicted AlphaFoldDB

No variants for Q9ZM10

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9ZM10

No associated diseases with Q9ZM10

4 regional properties for Q9ZM10

Type Name Position InterPro Accession
domain Polyphosphate kinase middle domain 117 - 322 IPR024953
domain Polyphosphate kinase N-terminal domain 4 - 108 IPR025198
domain Polyphosphate kinase C-terminal domain 2 500 - 664 IPR025200
domain Polyphosphate kinase, C-terminal domain 1 329 - 490 IPR041108

Functions

Description
EC Number 2.7.4.1 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
polyphosphate kinase complex A protein complex that possesses polyphosphate kinase activity.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
polyphosphate kinase activity Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
polyphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNRFFNRELS WLAFNTRVLN EAKDESLPLL ERLKFLAIYD TNLDEFYMIR VAGLKQLYEH
70 80 90 100 110 120
KIASKGIDGA SPEEQLEKIK HYLAHEIEER ELEFQKIQAL LFKKGLCITP YNELNLEQKA
130 140 150 160 170 180
KAKTYFKEQL YALVLPFKLD SSHTFPPLAN LTFALFAHIK DKETQSASYA LIKLPSFIFR
190 200 210 220 230 240
FVELEKGLFA LAEEIVEAHL EELFLEHEIL DCMAFRVTCD ADIAITEDEA HDYADLMSKS
250 260 270 280 290 300
LRKRNQGEIV RLQTQKGSQE LLKTLLASLR SFQTHSYKKH KLTGMHIYKS AIMLNLGDLW
310 320 330 340 350 360
ELVNHSDFKA LKSPNFTPKI HPHFNENDLF KSIEKQDLLL FHPYESFEPV IDLIEQAASD
370 380 390 400 410 420
PTTLSIKMTL YRVGKHSPIV KALIEAASKI QVSVLVELKA RFDEESNLHW AKALERAGAL
430 440 450 460 470 480
VVYGVFKLKV HAKMLVITKK TDNQLRHFTH LSTGNYNPLS AKIYTDVSFF SAKNEIANDI
490 500 510 520 530 540
IKLFHSLLTS SATSNTLETL FMAPKQIKPK IIELIQNEMN HKQEGYIILK ANALVDSEII
550 560 570 580 590 600
EWLYQASQKG VKIDLIIRGI CCLKPQVKGL SENIRVYSIV GKYLEHARIY YFKHENIYFS
610 620 630 640 650 660
SADLMPRNLE RRVELLIPAT NPKIANKLLH ILEIQLKDTL KRYELNSKGR YAKISNPNDP
670
LNSQDYFEKQ ALKTL