Q9ZL74

PR
Gene name
mobA
Protein name
Molybdenum cofactor guanylyltransferase
Names
MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase
Species
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
KEGG Pathway
hpj:jhp_0706
EC number
2.7.7.77: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

163-209 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9ZL74

Entry ID Method Resolution Chain Position Source
AF-Q9ZL74-F1 Predicted AlphaFoldDB

No variants for Q9ZL74

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9ZL74

No associated diseases with Q9ZL74

1 regional properties for Q9ZL74

Type Name Position InterPro Accession
domain MobA-like NTP transferase 11 - 151 IPR025877

Functions

Description
EC Number 2.7.7.77 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
metal ion binding Binding to a metal ion.
molybdenum cofactor guanylyltransferase activity Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor.

1 GO annotations of biological process

Name Definition
Mo-molybdopterin cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKNPIINNIP CVLLAGGKSS RFIINNIPIN KALMPLKSYP SLLEYQYTRL LKLFKQVIIS
70 80 90 100 110 120
AKKSYELNAP YLLEKEGGLF SPLFGIHNAF LTLQTPYIFF IAIDTPLVSF ESIKILCGIQ
130 140 150 160 170 180
NFSVVYAKSP TKEHYLISLW HQSILNALNY TLKTQNYRLS DLIKNASSTA IHFDKEEEFL
190 200
NLNTLKDYEL AVQILKEGSN GRRRKDRTP