Q9ZKS4

PR
Gene name
htpX
Protein name
Protease HtpX homolog
Names
Species
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
KEGG Pathway
hpj:jhp_0861
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

238-307 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9ZKS4

Entry ID Method Resolution Chain Position Source
AF-Q9ZKS4-F1 Predicted AlphaFoldDB

No variants for Q9ZKS4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9ZKS4

No associated diseases with Q9ZKS4

2 regional properties for Q9ZKS4

Type Name Position InterPro Accession
domain Cobalamin-independent methionine synthase MetE, C-terminal/archaeal 428 - 751 IPR002629
domain Cobalamin-independent methionine synthase MetE, N-terminal 5 - 312 IPR013215

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
metalloendopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTNFEKIIAQ NRLKTNAVLT TYCAIFAFIG LLVDAIRINA NDLGIALFKL MTFQIFPTIT
70 80 90 100 110 120
IVMFVVAFVI ILVCIQNFSS IMLSGDEYKL IDPSKVLSSK ENQIHRLLLE LLEEAKLHFE
130 140 150 160 170 180
PKLYIINAPY MNAFASGWDE SNSLIALTSA LIERLDRDEL KAVIAHELSH IRHNDIRLTM
190 200 210 220 230 240
CVGILSNIML LVANFSVYFF MGNRKNSGAN LARMILWVLQ IILPFLTLLL QMYLSRTREY
250 260 270 280 290 300
MADSGAAFLM HDNKPMIRAL QKISNDYTNN DYKEIDKNST RSAAYLFNAE MFSTHPSIKN
RIQSLRKRVI