Q9ZJ68
Gene name |
nhaA |
Protein name |
Na(+)/H(+) antiporter NhaA |
Names |
Sodium/proton antiporter NhaA |
Species |
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99) |
KEGG Pathway |
hpj:jhp_1447 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9ZJ68
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9ZJ68-F1 | Predicted | AlphaFoldDB |
No variants for Q9ZJ68
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9ZJ68 | |||||
No associated diseases with Q9ZJ68
No regional properties for Q9ZJ68
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9ZJ68 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| antiporter activity | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out). |
| sodium ion transmembrane transporter activity | Enables the transfer of sodium ions (Na+) from one side of a membrane to the other. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of pH | Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNLKKTENAL | SLTLKNFIKS | ESFGGIFLFL | NAVLAMVVAN | SFLKESYFAL | WHTPFGFQVG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DFFIGFSLHN | WIDDVLMALF | FLMIGLEIKR | ELLFGELSSF | KKASFPVIAA | IGGMIAPGLI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YFFLNANTPS | QHGFGIPMAT | DIAFALGVIM | LLGKRVPTAL | KVFLITLAVA | DDLGAIVVIA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LFYTTNLKFA | WLLGALGVVL | VLAILNRLNI | RSLIPYLLLG | VLLWFCVHQS | GIHATIAAVV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LAFMIPVKIP | KDSKNVELLE | LGKRYAETSS | GVLLTKEQQE | ILHSIEEKAS | ALQSPLERLE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HFLAPISGYF | IMPLFAFANA | GVSVDSSINL | EVDKVLLGVI | LGLCLGKPLG | IFLITFISEK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LKITARPKGI | GWWHILGAGL | LAGIGFTMSM | FISNLAFTSE | HKDAMEVAKI | AILLGSLISG |
| 430 | |||||
| IIGALYLFAL | DKRAALKK |