Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9ZF22
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9ZF22-F1 | Predicted | AlphaFoldDB |
No variants for Q9ZF22
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9ZF22 | |||||
No associated diseases with Q9ZF22
8 regional properties for Q9ZF22
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 416 - 585 | IPR000795 |
| domain | Translation elongation factor EFTu-like, domain 2 | 837 - 904 | IPR004161 |
| domain | Small GTP-binding protein domain | 419 - 575 | IPR005225 |
| domain | Translation initiation factor IF-2, N-terminal | 5 - 47 | IPR006847-1 |
| domain | Translation initiation factor IF-2, N-terminal | 340 - 390 | IPR006847-2 |
| domain | Initiation factor 2 associated domain, bacterial | 60 - 98 | IPR013575 |
| domain | Translation initiation factor IF- 2, domain 3 | 692 - 806 | IPR023115 |
| domain | Translation initiation factor IF-2, domain II | 592 - 685 | IPR044145 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTDETVKSLA | EEIQTPVERL | VQQFADAGIE | KTVSDSVSQK | EKETLLAWLN | RDKDISTGQP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SKLTLQRKVR | STLSVPGTGG | KSKSVAIEVR | KKRTYVNRDV | IEKSQAEEQA | LREAEEKAHR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EVEEKAQREA | QEKAQRAAEE | KAKREAQEAK | KQAEEKAKRE | AEEAKREAAE | LAKREAAEKN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KVKQNDKPKA | DVADQDKARR | NAELAELKRK | TEEAQRLKVE | EETRAAAEKA | RRLAEENAEK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| WTAEPKAPET | ESADYHVTTS | RYARDAEDES | DAEVEGDRRR | GRTAKAPRAK | KNNRHSEKAD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| REEARAAGRS | NKKGKRKSST | LQQGFHKPAV | AVNRDVIIGE | TISVAELANK | MAVKGSEVIK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TMMKMGAMAT | INQVLDQETA | QLVAEEMGHK | VILRRENELE | EQVMNDRDTG | EESEVSRAPV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VTIMGHVDHG | KTSLLDYIRS | TKVASGEAGG | ITQHIGAYHV | KTDKGEITFL | DTPGHAAFTS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| MRARGAQVTD | IVVLVVAADD | GVMPQTIEAI | QHAKAANVPV | VVAVNKIDKH | EADPDRVKTE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LSQYGILSED | WGGETQFMHV | SAKQGLGIDE | LLDAILLQAE | VLELKAVKEG | MASGVVIESY |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LDKGRGPVAT | ILVREGTLNK | GDIVLCGFEY | GRIRAMRNEL | GQEVQSAGPS | MPVEILGLSN |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VPSAGDEATV | VRDEKKAREV | ALYRQGKFRE | VKLARQQKSK | LENMFANMEE | GKVSELNIVL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| KTDVQGTCEA | ITDALVKLST | DEVKLRIIGS | GVGGITETDA | TLAAASEAII | LGFNVRADAS |
| 790 | 800 | 810 | 820 | 830 | 840 |
| ARRIIEQESV | DLRYYSVIYS | LIDEIKLAMS | GMLAPEYKQE | IMGLAEVRDV | FKSPKFGAVA |
| 850 | 860 | 870 | 880 | 890 | 900 |
| GCMVVEGNIK | RNNPIRVLRD | NVVIYEGELE | SLRRFKDDVN | EVRNGMECGI | GVKNYNDVRV |
| 910 | |||||
| GDMIEVFQVI | EIKRSIA |