Q9ZEL6

PR
Gene name
pilD
Protein name
Prepilin leader peptidase/N-methyltransferase
Names
Species
Pseudomonas stutzeri (Pseudomonas perfectomarina)
KEGG Pathway
EC number
3.4.23.43: Aspartic endopeptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

208-279 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9ZEL6

Entry ID Method Resolution Chain Position Source
AF-Q9ZEL6-F1 Predicted AlphaFoldDB

No variants for Q9ZEL6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9ZEL6

No associated diseases with Q9ZEL6

2 regional properties for Q9ZEL6

Type Name Position InterPro Accession
domain Prepilin type IV endopeptidase, peptidase domain 137 - 244 IPR000045
domain Peptidase A24A, N-terminal 20 - 126 IPR010627

Functions

Description
EC Number 3.4.23.43 Aspartic endopeptidases
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
aspartic-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
metal ion binding Binding to a metal ion.
methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.

2 GO annotations of biological process

Name Definition
methylation The process in which a methyl group is covalently attached to a molecule.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTPVEFLASN PLAFVLCALV LGLLVGSFLN VVIHRLPIMM QRDWQSQARE FLELPAEPAG
70 80 90 100 110 120
AAFNLFLPHS RCPHCDHQIR AWENIPLISW LALRGKCSAC KASISKRYPL VELACGLLSG
130 140 150 160 170 180
YVAWHFGFSW QAGAMLLLTW GLLAMSMIDV DHQLLPDSLV LPLLWLGLII NSFGLFASLE
190 200 210 220 230 240
DALWGAVVGY LALWSVYWLF KLVTGKEGMG YGDFKLLAML GAWGGWQVLP LTILLSSVVG
250 260 270 280
AVLGTVMLRM QKAESGTPIP FGPYLAIAGW VALLWGDQIT ASYLQFARL