Q9Z6R0

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Chlamydia pneumoniae (Chlamydophila pneumoniae)
KEGG Pathway
cpt:CpB1037
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

361-434 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9Z6R0

Entry ID Method Resolution Chain Position Source
AF-Q9Z6R0-F1 Predicted AlphaFoldDB

No variants for Q9Z6R0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9Z6R0

No associated diseases with Q9Z6R0

9 regional properties for Q9Z6R0

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 17 - 143 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 324 - 456 IPR001247-2
domain S1 domain 619 - 690 IPR003029
domain K Homology domain 552 - 617 IPR004087
domain K Homology domain, type 1 556 - 613 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 147 - 209 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 460 - 529 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 241 - 320 IPR015848
domain RNA-binding domain, S1 620 - 690 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNFQTISINL TEGKILVFET GKIARQANGA VLVRSGETCV FASACAVDLD DKVDFLPLRV
70 80 90 100 110 120
DYQEKFSSTG KTLGGFIKRE GRPSEKEILV SRLIDRSLRP SFPYRLMQDV QVLSYVWSYD
130 140 150 160 170 180
GQVLPDPLAI CAASAALAIS DIPQSNIVAG VRIGCIDNQW VINPTKTELA SSTLDLVLAG
190 200 210 220 230 240
TENAILMIEG HCDFFTEEQV LDAIEFGHKH IVTICKRLQL WQEEVGKSKN LSAVYPLPAE
250 260 270 280 290 300
VLTAVKECAQ DKFTELFNIK DKKVHAATAH EIEENILEKL QREDDDLFSS FNIKAACKTL
310 320 330 340 350 360
KSDTMRALIR DREIRADGRS LTTVRPITIE TSYLPRTHGS CLFTRGETQT LAVCTLGSEA
370 380 390 400 410 420
MAQRYEDLNG EGLSKFYLQY FFPPFSVGEV GRIGSPGRRE IGHGKLAEKA LSHALPDSAT
430 440 450 460 470 480
FPYTIRIESN ITESNGSSSM ASVCGGCLAL MDAGVPISSP IAGIAMGLIL DDQGAIILSD
490 500 510 520 530 540
ISGLEDHLGD MDFKIAGSGK GITAFQMDIK VEGITPAIMK KALSQAKQGC NDILNIMNEA
550 560 570 580 590 600
LSAPKADLSQ YAPRIETMQI KPTKIASVIG PGGKQIRQII EETGVQIDVN DLGVVSISAS
610 620 630 640 650 660
SASAINKAKE IIEGLVGEVE VGKTYRGRVT SVVAFGAFVE VLPGKEGLCH ISECSRQRIE
670 680 690
NISDVVKEGD IIDVKLLSIN EKGQLKLSHK ATLE