Q9Z6C9

PR
Gene name
cshA
Protein name
ATP-dependent RNA helicase CshA
Names
Autoaggregation-mediating protein
Species
Limosilactobacillus reuteri (Lactobacillus reuteri)
KEGG Pathway
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

333-497 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9Z6C9

Entry ID Method Resolution Chain Position Source
AF-Q9Z6C9-F1 Predicted AlphaFoldDB

No variants for Q9Z6C9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9Z6C9

No associated diseases with Q9Z6C9

6 regional properties for Q9Z6C9

Type Name Position InterPro Accession
domain 5'-3' exonuclease 29 - 304 IPR002421
domain XPG, N-terminal 1 - 107 IPR006085
domain XPG-I domain 146 - 233 IPR006086
conserved_site Helix-hairpin-helix motif, class 2 220 - 253 IPR008918
conserved_site XPG conserved site 79 - 93 IPR019974-1
conserved_site XPG conserved site 149 - 163 IPR019974-2

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Cytoplasm
  • Cell membrane ; Peripheral membrane protein ; Extracellular side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

2 GO annotations of biological process

Name Definition
RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
RNA secondary structure unwinding The process in which a secondary structure of RNA are broken or 'melted'.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKFSELGLSD SLLKAIKRSG YEEATPIQEQ TIPMVLEGKD VIGQAQTGTG KTAAFGLPII
70 80 90 100 110 120
ENVDTENPNI QAIIISPTRE LAIQTQEELY RLGKDKHVRV QVVYGGADIR RQIKSLKQHP
130 140 150 160 170 180
QILVGTPGRL RDHINRHTVK LDHIKTLVLD EADEMLNMGF LEDIESIIKE TPDDRQTLLF
190 200 210 220 230 240
SATMPPEIKR IGVQFMSDPE TVRIKAKELT TDLVDQYYVR ARDYEKFDIM TRLIDVQDPD
250 260 270 280 290 300
LTIVFGRTKR RVDELSKGLI ARGYNAAGIH GDLTQDKRSK IMWKFKNNEL DILVATDVAA
310 320 330 340 350 360
RGLDISGVTH VYNYDIPSDP DSYVHRIGRT GRAGHHGVSL TFVTPNEMDY LHEIEKLTRV
370 380 390 400 410 420
RMLPLKPPTA EEAFKGQVAS AFNDIDELIA QDSTDRYEEA AEKLLETHNA TDLVAALLNN
430 440 450 460 470 480
MTKEAASEVP VKITPERPLP RRNKRNNRNG NRNNSHGGNH YRRKNFRRHQ HGSHRNDNHG
490
KSHSSRHSFN IRHRKEN