Q9Z4J7
Gene name |
exaA |
Protein name |
Quinoprotein ethanol dehydrogenase |
Names |
QEDH, Quinoprotein alcohol dehydrogenase (cytochrome c), Quinoprotein alcohol dehydrogenase (cytochrome c550) |
Species |
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
KEGG Pathway |
pae:PA1982 |
EC number |
1.1.2.8: With a cytochrome as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q9Z4J7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1FLG | X-ray | 260 A | A/B | 35-616 | PDB |
| AF-Q9Z4J7-F1 | Predicted | AlphaFoldDB |
No variants for Q9Z4J7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9Z4J7 | |||||
No associated diseases with Q9Z4J7
10 regional properties for Q9Z4J7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Quinoprotein dehydrogenase, conserved site | 51 - 79 | IPR001479-1 |
| conserved_site | Quinoprotein dehydrogenase, conserved site | 282 - 303 | IPR001479-2 |
| repeat | Pyrrolo-quinoline quinone repeat | 82 - 278 | IPR002372-1 |
| repeat | Pyrrolo-quinoline quinone repeat | 532 - 568 | IPR002372-2 |
| repeat | Pyrrolo-quinoline quinone beta-propeller repeat | 97 - 129 | IPR018391-1 |
| repeat | Pyrrolo-quinoline quinone beta-propeller repeat | 147 - 178 | IPR018391-2 |
| repeat | Pyrrolo-quinoline quinone beta-propeller repeat | 192 - 235 | IPR018391-3 |
| repeat | Pyrrolo-quinoline quinone beta-propeller repeat | 361 - 397 | IPR018391-4 |
| repeat | Pyrrolo-quinoline quinone beta-propeller repeat | 452 - 517 | IPR018391-5 |
| repeat | Pyrrolo-quinoline quinone beta-propeller repeat | 527 - 558 | IPR018391-6 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.2.8 | With a cytochrome as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| outer membrane-bounded periplasmic space | The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| alcohol dehydrogenase (cytochrome c) activity | Catalysis of the reaction: 2 [Fe(III)cytochrome c] + a primary alcohol = 2 [Fe(II)cytochrome c] + an aldehyde + 2 H+. |
| calcium ion binding | Binding to a calcium ion (Ca2+). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| ethanol catabolic process | The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation. |
| ethanol oxidation | An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTRTSPAPA | GLLRPSLHCL | AFAVALGSAG | AALAKDVTWE | DIANDDKTTG | DVLQYGMGTH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AQRWSPLKQV | NADNVFKLTP | AWSYSFGDEK | QRGQESQAIV | SDGVIYVTAS | YSRLFALDAK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TGKRLWTYNH | RLPDDIRPCC | DVVNRGAAIY | GDKVFFGTLD | ASVVALNKNT | GKVVWKKKFA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DHGAGYTMTG | APTIVKDGKT | GKVLLIHGSS | GDEFGVVGRL | FARDPDTGEE | IWMRPFVEGH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MGRLNGKDST | VTGDVKAPSW | PDDRNSPTGK | VESWSHGGGA | PWQSASFDAE | TNTIIVGAGN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PGPWNTWART | AKGGNPHDYD | SLYTSGQVGV | DPSSGEVKWF | YQHTPNDAWD | FSGNNELVLF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DYKAKDGKIV | KATAHADRNG | FFYVVDRSNG | KLQNAFPFVD | NITWASHIDL | KTGRPVEREG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QRPPLPEPGQ | KHGKAVEVSP | PFLGGKNWNP | MAYSQDTGLF | YVPANHWKED | YWTEEVSYTK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GSAYLGMGFR | IKRMYDDHVG | SLRAMDPVSG | KVVWEHKEHL | PLWAGVLATA | GNLVFTGTGD |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GYFKAFDAKS | GKELWKFQTG | SGIVSPPITW | EQDGEQYLGV | TVGYGGAVPL | WGGDMADLTR |
| 610 | 620 | ||||
| PVAQGGSFWV | FKLPSWDNRT | ASR |