Q9YHY6

PR
Gene name
ncapd2 (capd2, cnap1, eg7)
Protein name
Condensin complex subunit 1
Names
Chromosome assembly protein XCAP-D2, Chromosome condensation-related SMC-associated protein 1, Chromosome-associated protein D2, Eg7, Non-SMC condensin I complex subunit D2
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:398080
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

526-607 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9YHY6

Entry ID Method Resolution Chain Position Source
AF-Q9YHY6-F1 Predicted AlphaFoldDB

No variants for Q9YHY6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9YHY6

No associated diseases with Q9YHY6

2 regional properties for Q9YHY6

Type Name Position InterPro Accession
domain Condensin complex subunit 1, N-terminal 74 - 236 IPR024324
domain Condensin complex subunit 1, C-terminal 1047 - 1207 IPR032682

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cytoplasm
  • Chromosome
  • In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin
  • A subpopulation of the complex however remains associated with chromosome foci in interphase cells
  • During mitosis, most of the condensin complex is associated with the chromatin
  • At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation
  • Dissociation from chromosomes is observed in late telophase
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
mitotic chromosome condensation The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTFHFHIPLA FRDLLKSGGI GQYVVQEVLP VRHVDAQFAA FQTSFRTEAP LCILQHFDTL
70 80 90 100 110 120
YSILHHFRSL DIAIKEDVLE VMVKVASRHA NELPAILEDL NLSVPQRAAH LNALKMNCFI
130 140 150 160 170 180
LTQLIEAFEA ETYKASLGSV EPSGKGKKAK SKPEGFSWES ERESILQALT HLLQLDIRRL
190 200 210 220 230 240
WSMSVVEEEF VSMMTSCCYK MMENPNIVMA KNKSTREALG HLLGVTVKRY NHMLSASVKV
250 260 270 280 290 300
IQLLQHFEHL ASVLVHTVSL WATEYGMKPV IGEIMREIGQ KCSQDLSRES SGFKAFATFL
310 320 330 340 350 360
TELAERIPAI MMPSISVLLD YLDGENYMMR NSVLTVMGEM VVRVLSGDQL EEAEKSSRDQ
370 380 390 400 410 420
FLDTLQEHLH DVNTYVRSCV IQIYNRIVQE KALPLSRFQS VVTLVVGRLF DKSVNVCKNA
430 440 450 460 470 480
IQLLASFLAN NPFTCKLSSV DLKVPLEKET KKLKEMREKY QGPKPVVVIS PEEEWEAMLP
490 500 510 520 530 540
EVLEAFKILQ QESKEEEDIE TEEIESSQHL REQILILLRK TSYKNSIRLT QKGIERFQED
550 560 570 580 590 600
PLFSEGDSEA KSELGILEKI FTEKKADLEQ PTTKDQDDAQ VNPTSEELPS QEVQNSDMDK
610 620 630 640 650 660
QEMLVQYLSD AHHFALKIEE AIDVISKMMY ETAVSVVQEV IEFFVTVSQF GVSQALLGVR
670 680 690 700 710 720
RMLPLVWSKE PGVREAVLSA YRRLYLSSNG ESERVKAQAL VRSLSLLMVD SSAGILQCLE
730 740 750 760 770 780
EIVSEFVQKG DIHPSVIQLL WEKFTQKSPC SEFERRAAVM LLGMMTRGQP EIVMSNLDTL
790 800 810 820 830 840
VSVGLGEQVQ KDYQLAREVC NCILKITDSQ KQTLGKSTEP FRLPKDHSLF VCLTEAVAGG
850 860 870 880 890 900
IGLSGLHWLP FKETAVRLVY ELGEEPEEIC SEILLRCSQN VLDGHQTQDE VPNVPAFLLT
910 920 930 940 950 960
HLLSLAGDVA LQQVVHLERA VSAELRRRRV LKEEQEAEKV GKQRKSKANE STMEEELGLV
970 980 990 1000 1010 1020
GASADDIEAE LIRKICDTEL LGGQQYLSAF LPLILRICNN PGRYSDPDLC TVATLALAKY
1030 1040 1050 1060 1070 1080
MMISSDFCDT HLRLLFTLLE KSPLPSVRSN IMIALGDLSI RFPNLIEPWT PNLYARLRDP
1090 1100 1110 1120 1130 1140
SREVRKTAGM VMTHLILKDM VKVKGQVSEM AVLLIESDQE ISALARNFFN ELSNKGNAVY
1150 1160 1170 1180 1190 1200
NLLPDIISRL SDPDCGVEEE AFRTIMKQLL SYITKDKQTE SLVEKMCHRF RTARTERQWR
1210 1220 1230 1240 1250 1260
DLAHCLSLLP FSEKGLRKMQ DCFDCYGDKL SDEAVYNSFL TTVAKMRRGA KPELKALIDE
1270 1280 1290 1300 1310 1320
FEQKLSRCHN KGLENMDVPE EPSAESDAQP PKAKRPPLAS VNVKKGKSED DFQTPKPPAS
1330 1340 1350 1360
RKSRRKVAVN FSSDEESDLE AELSEAETPK NPTPIRRTAR SRAK