Q9YEU2
Gene name |
pyk (APE_0489) |
Protein name |
Pyruvate kinase |
Names |
PK |
Species |
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) |
KEGG Pathway |
ape:APE_0489 |
EC number |
2.7.1.40: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9YEU2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9YEU2-F1 | Predicted | AlphaFoldDB |
No variants for Q9YEU2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9YEU2 | |||||
No associated diseases with Q9YEU2
1 regional properties for Q9YEU2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Pyruvate kinase, barrel | 5 - 333 | IPR015793 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.40 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| kinase activity | Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| potassium ion binding | Binding to a potassium ion (K+). |
| pyruvate kinase activity | Catalysis of the reaction: = ADP + H(+) + phosphoenolpyruvate => ATP + pyruvate. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRGPVKIVAT | VGPSSSSASI | LAQMLSLGVD | VARINASHGG | VEQWNSMLES | LRRAEEAVGK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RVGVAVDLEG | PRVRTGNSEP | VKLEKGDLVT | LGFMEGDVPV | DARQFFETID | EGDIVLLDDG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KIILQVESVE | GFRVKARVLE | GGVLGPRKGV | VVRGKEPDLP | PLSAKDRRAL | EFFADKGVSH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VYVSFARSAE | HVEKVRTVVR | RLGLRQARIF | AKIEGPSGVS | RIGEIAEASD | GVIIARGDLG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MHYSLEELPE | IQELIVWEAR | KRYKTVVLAT | EFLSSMIEKP | VPTRSEVVDI | YQAVLQTADA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LMLTGETAIG | KYPVKSVQWM | AKISSRAYKK | LATSPPERPR | PTSTPYKLAL | GLVELAESLD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SPLVVYSKTG | RFAERLASFK | PLKTFYVGVP | SREVERVVRH | LWGAEPIVVG | DYPYEAGLAK |
| 430 | 440 | 450 | |||
| TYEKLRRENI | IHGDETVVEA | AWSSERGIYI | IRVRNLEF |