Q9YBF8
Gene name |
glyS |
Protein name |
Glycine--tRNA ligase |
Names |
Glycyl-tRNA synthetase, GlyRS |
Species |
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) |
KEGG Pathway |
ape:APE_1639 |
EC number |
6.1.1.14: Ligases forming aminoacyl-tRNA and related compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9YBF8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9YBF8-F1 | Predicted | AlphaFoldDB |
No variants for Q9YBF8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9YBF8 | |||||
No associated diseases with Q9YBF8
No regional properties for Q9YBF8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9YBF8 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 6.1.1.14 | Ligases forming aminoacyl-tRNA and related compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| glycine-tRNA ligase activity | Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). |
| protein dimerization activity | The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glycyl-tRNA aminoacylation | The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEDLFEKLV | EIGKRRGFFW | PSYEIYGGVA | GFYDWGPLGH | LLKRRIIEKW | RRYFVLMHQD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HVVEIETPVI | GPEKVYIASG | HVEHFTDPIV | RCTSCGRTFR | ADHLVEEALG | INAEGLSVSE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LDRIIRERGL | RCPVCQGELG | RVETFNLLFR | TQIGPYEGSV | GYLRPELAQG | IFVAFKRVYE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AMRSRIPLGI | AQVGRVGRNE | ISPRQALVRL | REFTIMEMEY | FIDPEDQWGS | CPFFHRMADS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KLPILTYEAK | RRGEEKPESF | KLEEAVNEGV | VISPCLGYWM | AVGMRFVEDL | GVPSDSIMFE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EKGPEERAHY | SSQTFDQLVK | VSRWGWIEVA | GHSYRGDYDL | SRHMKYSGQD | LTAFKPYPKP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IVVKKRRVVV | DKAAIGRALK | SRAKTVLEEL | GRMGEGELER | LAASNRAVVA | GVELPPGSLR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IVEVEEKVSG | RRFVPHVVEP | SFGTDRNVYV | ALEYAYREVE | GRVVLAFPRD | IAPVQAVVLP |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LVENDEKLVE | RARMVYETLV | EAGFTVYYDD | SGSIGRRYAR | ADEIGVPAAV | TIDYQTLEDG |
| 550 | 560 | 570 | 580 | ||
| TVTLRDRDTW | RQVRIGADEV | VDKLRRFIYD | GARLEDLGTP | VKP |