Q9YAF1

PR
Gene name
prf1 (APE_1988.1)
Protein name
Peptide chain release factor subunit 1
Names
Translation termination factor aRF1
Species
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
KEGG Pathway
ape:APE_1988.1
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

143-214 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q9YAF1

Entry ID Method Resolution Chain Position Source
3AGK X-ray 210 A A 1-373 PDB
3VMF X-ray 230 A B 1-373 PDB
AF-Q9YAF1-F1 Predicted AlphaFoldDB

No variants for Q9YAF1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9YAF1

No associated diseases with Q9YAF1

3 regional properties for Q9YAF1

Type Name Position InterPro Accession
domain eRF1 domain 1/Pelota-like 8 - 138 IPR005140
domain eRF1 domain 2 143 - 274 IPR005141
domain eRF1 domain 3 282 - 370 IPR005142

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
translation release factor activity, codon specific A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQGRLEERL TISKRELARL LKELKKWSAP ATVLLSLYIP PGRPLSDVMT LLRQEYSITD
70 80 90 100 110 120
NIKLKRTRQA VKRALSAAMD RLQMLTSTPP NGLVLFCGED MSTGKFECFM FSPPEPIRVF
130 140 150 160 170 180
YYRTDKRFIT DFLEDMVEDN NAIGIIIVER DQATIGLLKG ARLEVLKELE GFVPGKHKMG
190 200 210 220 230 240
GQSQRRYERI IEQMVDEFFK KVGEEASNLL VPLAEKGVLK GVIVAGPGLA KQEFVEGNYL
250 260 270 280 290 300
DYRLKKILAP ELVDVAYQGL QGLKEAVMKA EKVVEAQMYR DAVNAMEEFK LHLAKGTGMI
310 320 330 340 350 360
VYGEKDVEAA LEMGAVKTLL IHESREDLEE WVEKAKSSGA QVIVVPESLA EAEWFLKTFG
370
GLAGILRFRI STV