Q9XT87
Gene name |
LDHA |
Protein name |
L-lactate dehydrogenase A chain |
Names |
LDH-A, LDH muscle subunit, LDH-M |
Species |
Monodelphis domestica (Gray short-tailed opossum) |
KEGG Pathway |
mdo:503513 |
EC number |
1.1.1.27: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9XT87
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9XT87-F1 | Predicted | AlphaFoldDB |
No variants for Q9XT87
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9XT87 | |||||
No associated diseases with Q9XT87
1 regional properties for Q9XT87
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Amine oxidase | 23 - 460 | IPR002937 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.1.27 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| L-lactate dehydrogenase activity | Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| carboxylic acid metabolic process | The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGTVKDQLIL | NVLKEEQTPH | NKITVVGVGA | VGMACAISIL | MKDLADELAL | VDVIEDKLKG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EMMDLQHGSL | FLKTPKIVSS | KDYAVTANSK | LVVITAGARQ | QEGESRLNLV | QRNVNIFKFI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IPNIVKYSPN | CKLLVVSNPV | DILTYVAWKL | SGFPKNRVIG | SGCNLDSARF | RYLMGEKLGI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HSSSCHGWIL | GEHGDSSVPV | WSGVNVAGVS | LKSLHPALGT | DSDSEQWKDV | HKQVVESAYE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VIKLKGYTSW | AIGLSVADLA | ESIMKNLRRV | HPISTMIKGL | YGINEDVFLS | VPCILGQNGI |
| 310 | 320 | 330 | |||
| SDVVKVTLTT | EEESRLKQSA | DTLWGIQKEL | QF |