Q9XES0

PR
Gene name
DXR
Protein name
1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic
Names
1-deoxyxylulose-5-phosphate reductoisomerase, DXP reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase
Species
Mentha piperita (Peppermint) (Mentha aquatica x Mentha spicata)
KEGG Pathway
EC number
1.1.1.267: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

12-95 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9XES0

Entry ID Method Resolution Chain Position Source
AF-Q9XES0-F1 Predicted AlphaFoldDB

No variants for Q9XES0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9XES0

No associated diseases with Q9XES0

3 regional properties for Q9XES0

Type Name Position InterPro Accession
domain 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal 77 - 205 IPR013512
domain 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal 219 - 302 IPR013644
domain DXP reductoisomerase C-terminal domain 334 - 454 IPR026877

Functions

Description
EC Number 1.1.1.267 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

3 GO annotations of molecular function

Name Definition
1-deoxy-D-xylulose-5-phosphate reductoisomerase activity Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH.
metal ion binding Binding to a metal ion.
NADPH binding Binding to the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.

1 GO annotations of biological process

Name Definition
isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAPTEIKTLS FLDSSKSNYN LNPLKFQGGF AFKRKDSGCT AAKRVHCSAQ SQSPPPAWPG
70 80 90 100 110 120
RAFPEPGRMT WEGPKPISVI GSTGSIGTQT LDIVAENPDK FRIVALAAGS NVTLLADQVK
130 140 150 160 170 180
AFKPKLVSVK DESLISELKE ALAGFEDMPE IIPGEQGMIE VARHPDAVTV VTGIVGCAGL
190 200 210 220 230 240
KPTVAAIEAG KDIALANKET LIAGGPFVLP LAKKHNVKIL PADSEHSAIF QCIQGLPEGA
250 260 270 280 290 300
LRRIILTASG GAFRDLPVEK LKEVKVADAL KHPNWNMGKK ITVDSATLFN KGLEVIEAHY
310 320 330 340 350 360
LFGAEYDDIE IVIHPQSIIH SMVETQDSSV LAQLGWPDMR LPILYTLSWP ERIYCSEITW
370 380 390 400 410 420
PRLDLCKVDL TFKKPDNVKY PSMDLAYAAG RAGGTMTGVL SAANEKAVEM FIDEKIGYLD
430 440 450 460
IFKVVELTCD KHRSEMAVSP SLEEIVHYDQ WARDYAATVL KSAGLSPALV