Q9WZS2
Gene name |
norM (TM_0815) |
Protein name |
Probable multidrug resistance protein NorM |
Names |
Multidrug-efflux transporter |
Species |
Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) |
KEGG Pathway |
tmw:THMA_0834 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9WZS2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9WZS2-F1 | Predicted | AlphaFoldDB |
No variants for Q9WZS2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9WZS2 | |||||
No associated diseases with Q9WZS2
No regional properties for Q9WZS2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9WZS2 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| antiporter activity | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out). |
| xenobiotic transmembrane transporter activity | Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| ion transport | The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRYSLFKNYL | PKEEVPEIRK | ELIKLALPAM | GENVLQMLFG | MADTAFLGHY | SWKAMSGVGL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SNQVFWVVQV | VLIAASMGAT | VTIANAIGAG | NRKAVRSLAW | NSVFLAIFTG | VILTALTPLS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DVLINIFPNL | EGEIESSAKE | YLKVILSGSM | GFSIMAVFSA | MLRGAGDTRT | PMIVTGLTNF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LNIFLDYAMI | FGKFGFPEMG | VRGAAVATIL | SRFVGAGILT | YVIFKREEFQ | LRKGLVPPKW |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SSQKEILRVG | FPTAIENFVF | STGVLMFANI | LLIAGAEAYA | GHRIGINVES | LSFMPAFGIS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VAITTLVGRY | NGMGNKEHVL | GVIRQGWILS | LLFQVTVGII | IFLFPEPLIR | IFTSDPQIIE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ISKLPVKIIG | LFQFFLAIDS | TMNGALRGTG | NTLPPMIITF | ISIWTARLPV | AFVMVKYFQL |
| 430 | 440 | 450 | 460 | ||
| GLLGAWIGMI | ADIIFRSTLK | LLFFLSGKWE | KRAVLTRERV | KELG |