Q9WZP2

PR
Gene name
enc
Protein name
Type 1 encapsulin shell protein
Names
Maritimacin, Thermotoga bacteriocin
Species
Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
KEGG Pathway
tma:TM0785
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

67-139 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

13 structures for Q9WZP2

Entry ID Method Resolution Chain Position Source
3DKT X-ray 310 A A/B/C/D/E/F/G/H/I/J 1-265 PDB
6WKV EM 299 A 0/1/2/3/4/5/6/7/8/9/A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T 1-265 PDB
7K5W EM 287 A A 1-265 PDB
7KQ5 EM 200 A A 1-265 PDB
7LII EM 355 A A 1-265 PDB
7LIJ EM 284 A A 1-265 PDB
7LIK EM 291 A A 1-265 PDB
7LIL EM 284 A A 1-265 PDB
7LIM EM 275 A A 1-265 PDB
7LIS EM 296 A A 1-265 PDB
7LIT EM 253 A A 1-265 PDB
7MU1 EM 330 A A 1-264 PDB
AF-Q9WZP2-F1 Predicted AlphaFoldDB

No variants for Q9WZP2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9WZP2

No associated diseases with Q9WZP2

4 regional properties for Q9WZP2

Type Name Position InterPro Accession
domain K Homology domain, type 2 218 - 297 IPR004044
domain Small GTP-binding protein domain 22 - 181 IPR005225
domain GTP binding domain 24 - 138 IPR006073
domain Era-type guanine nucleotide-binding (G) domain 19 - 187 IPR030388

Functions

Description
EC Number
Subcellular Localization
  • Encapsulin nanocompartment
  • Globular particles 19-20 nm, with 60-80 nm long tails (Probable)
  • Shells are 23-24 nm in diameter, walls are 2
  • 0-2
  • 5 nm thick (PubMed:19172747)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
encapsulin nanocompartment Intracellular non-membrane bound organelle, consisting of proteinaceous polyhedral shells that encapsulate enzymes, protecting the contents from their surrounding milieu and/or the milieu from reactants in their interior. The self-assembling, 25-42 nm nanocompartment shell, unlike larger bacterial microcompartments, is made of only one protein, and has only a few proteins inside. Shells about vary from about 25-42 nm in diameter. The shell protein has an HK97-like fold and probably evolved from a viral protein. Artificial encapsulin nanocompartments can be expressed and filled with cargo proteins for biotechnological uses. They are found in many bacterial and a few archaeal phyla.

1 GO annotations of molecular function

Name Definition
peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

3 GO annotations of biological process

Name Definition
cellular iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
ion transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEFLKRSFAP LTEKQWQEID NRAREIFKTQ LYGRKFVDVE GPYGWEYAAH PLGEVEVLSD
70 80 90 100 110 120
ENEVVKWGLR KSLPLIELRA TFTLDLWELD NLERGKPNVD LSSLEETVRK VAEFEDEVIF
130 140 150 160 170 180
RGCEKSGVKG LLSFEERKIE CGSTPKDLLE AIVRALSIFS KDGIEGPYTL VINTDRWINF
190 200 210 220 230 240
LKEEAGHYPL EKRVEECLRG GKIITTPRIE DALVVSERGG DFKLILGQDL SIGYEDREKD
250 260
AVRLFITETF TFQVVNPEAL ILLKF