Q9WZE6

PR
Gene name
fliM
Protein name
Flagellar motor switch protein FliM
Names
Species
Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
KEGG Pathway
tma:TM0679
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-78 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

6 structures for Q9WZE6

Entry ID Method Resolution Chain Position Source
2HP7 X-ray 200 A A 44-226 PDB
3SOH X-ray 350 A A/C 46-233 PDB
4FHR X-ray 193 A A 46-230 PDB
4IGA X-ray 173 A B 1-20 PDB
4QRM X-ray 432 A A/C/E/G/I/K/M/O/Q/S/U 46-228 PDB
AF-Q9WZE6-F1 Predicted AlphaFoldDB

No variants for Q9WZE6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9WZE6

No associated diseases with Q9WZE6

3 regional properties for Q9WZE6

Type Name Position InterPro Accession
conserved_site GTP cyclohydrolase I, conserved site 95 - 111 IPR018234-1
conserved_site GTP cyclohydrolase I, conserved site 143 - 153 IPR018234-2
domain GTP cyclohydrolase I domain 37 - 214 IPR020602

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein
  • Bacterial flagellum basal body
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
bacterial-type flagellum basal body One of the three major substructures of the bacterial-type flagellum, the basal body is embedded in the cell envelope (the plasma membrane, peptidoglycan cell wall, and, if one is present, the outer membrane); it houses the secretion apparatus that exports the more distal components and the flagellar motor.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
cytoskeletal motor activity Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force).

2 GO annotations of biological process

Name Definition
bacterial-type flagellum-dependent cell motility Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.
positive chemotaxis The directed movement of a motile cell or organism towards a higher concentration of a chemical.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDVLSQEEI NQLIEALMKG ELKEEDLLKE EEEKKVKPYD FKRPSKFSKE QLRTFQMIHE
70 80 90 100 110 120
NFGRALSTYL SGRLRTFVDV EISIDQLTYE EFIRSVMIPS FIVIFTGDVF EGSAIFEMRL
130 140 150 160 170 180
DLFYTMLDII MGGPGENPPN RPPTEIETSI MRKEVTNMLT LLAQAWSDFQ YFIPSIENVE
190 200 210 220 230 240
TNPQFVQIVP PNEIVLLVTA SVSWGEFTSF INVCWPFSLL EPLLEKLSDR FWMMGRKPEK
250 260 270 280 290 300
VEERMEELRK ASQKIPVTVQ AVIGETELRL KEILDLEVGD VIRLGTHYKD EIRIDVEGRP
310 320
KFRGIPGVFK GKYAVKVTGE FTNGGEYE