Q9WY63

PR
Gene name
fliG (TM_0220)
Protein name
Flagellar motor switch protein FliG
Names
Species
Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
KEGG Pathway
tma:TM0220
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

149-226 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

8 structures for Q9WY63

Entry ID Method Resolution Chain Position Source
1LKV X-ray 280 A X 104-335 PDB
1QC7 X-ray 220 A A/B 235-335 PDB
3AJC X-ray 230 A A 104-335 PDB
3SOH X-ray 350 A B/D 117-193 PDB
4FHR X-ray 193 A B 115-327 PDB
4QRM X-ray 432 A B/D/F/H/J/L/N/P/R/T/V 117-187 PDB
5TDY X-ray 210 A B/D 1-98 PDB
AF-Q9WY63-F1 Predicted AlphaFoldDB

No variants for Q9WY63

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9WY63

No associated diseases with Q9WY63

3 regional properties for Q9WY63

Type Name Position InterPro Accession
domain Flagellar motor switch protein FliG, C-terminal 219 - 325 IPR023087
domain Flagellar motor switch protein FliG, N-terminal domain 6 - 108 IPR028263
domain Flagellar motor switch protein FliG, middle domain 116 - 189 IPR032779

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Bacterial flagellum basal body
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
bacterial-type flagellum basal body One of the three major substructures of the bacterial-type flagellum, the basal body is embedded in the cell envelope (the plasma membrane, peptidoglycan cell wall, and, if one is present, the outer membrane); it houses the secretion apparatus that exports the more distal components and the flagellar motor.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
cytoskeletal motor activity Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force).
protein heterodimerization activity Binding to a nonidentical protein to form a heterodimer.
protein homodimerization activity Binding to an identical protein to form a homodimer.

2 GO annotations of biological process

Name Definition
bacterial-type flagellum-dependent cell motility Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.
chemotaxis The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPEKKIDGRR KAAVLLVALG PEKAAQVMKH LDEETVEQLV VEIANIGRVT PEEKKQVLEE
70 80 90 100 110 120
FLSLAKAKEM ISEGGIEYAK KVLEKAFGPE RARKIIERLT SSLQVKPFSF VRDTDPVQLV
130 140 150 160 170 180
NFLQSEHPQT IAVVLSYLDP PVAAQILGAL PEELQTEVLK RIALLERTSP EVVKEIERNL
190 200 210 220 230 240
EKKISGFVSR TFSKVGGIDT AAEIMNNLDR TTEKKIMDKL VQENPELADE IRRRMFVFED
250 260 270 280 290 300
ILKLDDRSIQ LVLREVDTRD LALALKGASD ELKEKIFKNM SKRAAALLKD ELEYMGPVRL
310 320 330
KDVEEAQQKI INIIRRLEEA GEIVIARGGG EELIM