Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9WU45
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9WU45-F1 | Predicted | AlphaFoldDB |
No variants for Q9WU45
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9WU45 | |||||
No associated diseases with Q9WU45
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloride channel complex | An ion channel complex through which chloride ions pass. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| voltage-gated chloride channel activity | Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of aldosterone biosynthetic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. |
| regulation of ion transmembrane transport | Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAASAAAAGE | GMEPRALQYE | QTLMYGRYTQ | ELGAFAKEEA | ARIRLGGPEP | WKGPPSPRVP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PELLEYGQSR | CAPCCICSVR | CHKFLVSRVG | EDWIFLVLLG | LLMALVSWAM | DYAIAVCLQA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QQWMSQGLNT | NILLQYLAWV | TYPVVLITFS | AGFTQILAPQ | AVGSGIPEMK | TILRGVVLKE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YLTLKTFVAK | VIGLTCALGS | GMPLGKEGPF | VHIASMCASL | LSKFLSLFGG | IYENESRNTE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MLAAACAVGV | GCCFAAPIGG | VLFSIEVTST | FFAVRNYWRG | FFSATFSAFI | FRVLAVWNRD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EETITALFKT | RFRLDFPFDL | QELPAFAVIG | IASGFGGALF | VYLNRKIVQV | MRKQKTINRF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LMRKRLLFPA | LVTLLISTLT | FPPGFGQFMA | GQLSQKETLV | TLFDNRTWVH | QGLVEEQEPP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| STSQAWNPPR | ANVFLTLVIF | ILMKFWMSAL | ATTIPVPCGA | FMPVFVIGAA | FGRLVGESMA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AWFPDGIHTD | GSTYRIVPGG | YAVVGAAALA | GAVTHTVSTA | VIVFELTGQI | AHILPVMIAV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ILANAVAQSL | QPSLYDSIIR | IKKLPYLPEL | GWGRHQQYRV | RVEDIMVRDV | PYVALNCTFR |
| 610 | 620 | 630 | 640 | 650 | 660 |
| DLRLALHRTK | GRMLALVESS | ESMILLGSIE | RSQVVTLLGA | QLSAARRRQH | IQERRKAQMS |
| 670 | 680 | 690 | 700 | 710 | 720 |
| PPSDQDGLPS | PESSVHFQVN | TEDSAFIPAR | GETHKPLKPA | LKRGPSNASK | AGETSTGSME |
| 730 | 740 | 750 | 760 | 770 | 780 |
| SAGIALRSLF | CGSPPPEATS | DLEKPESCER | RKLKRVRISL | ANDADLEGEM | SPEEILEWEE |
| 790 | 800 | 810 | 820 | 830 | 840 |
| QQLNEPVNFS | DCKIDPAPFQ | LVERTSLHKT | HTIFSLLGVD | HAYVTSIGRL | IGIVTLKELR |
| 850 | 860 | 870 | 880 | 890 | 900 |
| KAIEGSVTAQ | GVKVRPPLAS | FRDSATSSSD | TETTEVHALW | GPHSCHGLPR | DGSPSDSDDK |
| CQ |