Q9W7E8

PR
Gene name
koza
Protein name
Homeobox protein koza
Names
Homeodomain transcription factor koza
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:373737
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

37-124 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9W7E8

Entry ID Method Resolution Chain Position Source
AF-Q9W7E8-F1 Predicted AlphaFoldDB

No variants for Q9W7E8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9W7E8

No associated diseases with Q9W7E8

4 regional properties for Q9W7E8

Type Name Position InterPro Accession
domain Homeobox domain 100 - 164 IPR001356
conserved_site Homeobox, conserved site 135 - 158 IPR017970
domain Homeobox domain, metazoa 124 - 135 IPR020479-1
domain Homeobox domain, metazoa 139 - 158 IPR020479-2

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.

2 GO annotations of biological process

Name Definition
positive regulation of transcription by RNA polymerase II Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKLRTEDMS HPVKPLRSFL IQDILSHMGP GSKEKSLGFP KTDQDQDSSL RDTEEKYASE
70 80 90 100 110 120
KLQSSSQPAE IHHSHMEADE NLELDTAQPI TAVENKLAKQ QQKRSRAAFS HSQVIELERK
130 140 150 160 170 180
FSSQKYLSAP ERAQLAKSLK LTETQVKIWF QNRRYKTKRK QLATDMEEVE KSSAHPAQCR
190 200 210
DTNISRTSLL SFYQNYQRYP YLYYLAGWPA PLW