Q9W3C2
Gene name |
CG1785 |
Protein name |
Ribosome biogenesis protein NOP53 |
Names |
|
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG1785 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9W3C2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9W3C2-F1 | Predicted | AlphaFoldDB |
No variants for Q9W3C2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9W3C2 | |||||
No associated diseases with Q9W3C2
No regional properties for Q9W3C2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9W3C2 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| 5S rRNA binding | Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| ribosomal large subunit assembly | The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit. |
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9NZM5 | NOP53 | Ribosome biogenesis protein NOP53 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTAVEPATKK | KRISKKNKSA | WRKTDIQDVE | QFLEDQRQEE | RVGTFADKQD | EDLFVVDSSL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PKTKATVLSV | KQKRKLNAKK | PMRSYQALEN | TSKVQDPIAK | RNHVRQKKNG | RNIELEVCNP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TKPRHRQANS | DRAQYYVKLE | QRLADKKNKK | LDVEKDIWQE | VDFRDEIPGL | KDEKGWISRE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LALHTAGNIG | KKVVKTHASL | HHKTTKAKKF | ELPHPGMSYN | PAPEDHQALI | DQVVEREEGI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IKKEQHLKRV | TTSMFSKVTP | EERDRRRLNE | MSQGMDEEEG | SELDEDVQTN | GKKKEDDDEK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PYHTINAPVE | NKKKSKQARR | NELKQKELAR | QTELKRKLKQ | QTADLIRIKS | IRHELDDEEE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DLNDLKKRRK | QRAEKAKFEP | KRLGRHKFEE | PDLDVNLPED | IAGNLRNVKT | ESSLLKDRFH |
| 430 | 440 | 450 | 460 | 470 | |
| TLQRNNMLPT | TKLVSRKKSK | VKRFERNSHK | EPGVSYNDLK | ERRRAAAAAA | KATANIKI |