Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9W0M2

Entry ID Method Resolution Chain Position Source
AF-Q9W0M2-F1 Predicted AlphaFoldDB

No variants for Q9W0M2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9W0M2

No associated diseases with Q9W0M2

No regional properties for Q9W0M2

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9W0M2

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
sweet taste receptor activity Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste.
taste receptor activity Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste.

4 GO annotations of biological process

Name Definition
sensory perception of chemical stimulus The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
sensory perception of sweet taste The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
sensory perception of taste The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P83296 Gr64e Gustatory receptor for sugar taste 64e Drosophila melanogaster (Fruit fly) PR
10 20 30 40 50 60
MSRTSDDIRK HLKVRRQKQR AILAMRWRCA QGGLEFEQLD TFYGAIRPYL CVAQFFGIMP
70 80 90 100 110 120
LSNIRSRDPQ DVKFKVRSIG LAVTGLFLLL GGMKTLVGAN ILFTEGLNAK NIVGLVFLIV
130 140 150 160 170 180
GMVNWLNFVG FARSWSHIML PWSSVDILML FPPYKRGKRS LRSKVNVLAL SVVVLAVGDH
190 200 210 220 230 240
MLYYASGYCS YSMHILQCHT NHSRITFGLY LEKEFSDIMF IMPFNIFSMC YGFWLNGAFT
250 260 270 280 290 300
FLWNFMDIFI VMTSIGLAQR FQQFAARVGA LEGRHVPEAL WYDIRRDHIR LCELASLVEA
310 320 330 340 350 360
SMSNIVFVSC ANNVYVICNQ ALAIFTKLRH PINYVYFWYS LIFLLARTSL VFMTASKIHD
370 380 390 400 410 420
ASLLPLRSLY LVPSDGWTQE VQRFADQLTS EFVGLSGYRL FCLTRKSLFG MLATLVTYEL
430
MLLQIDAKSH KGLRCA