Q9VNP5
Gene name |
BoYb (CG11133) |
Protein name |
Putative ATP-dependent RNA helicase BoYb |
Names |
Brother of Yb |
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG11133 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9VNP5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9VNP5-F1 | Predicted | AlphaFoldDB |
No variants for Q9VNP5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9VNP5 | |||||
No associated diseases with Q9VNP5
1 regional properties for Q9VNP5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Helicase superfamily 1/2, ATP-binding domain | 87 - 263 | IPR014001 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| Yb body | A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| germ-line stem cell division | The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes. |
| meiotic cell cycle | Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. |
| negative regulation of transposition, RNA-mediated | Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VL52 | SoYb | Putative ATP-dependent RNA helicase SoYb | Drosophila melanogaster (Fruit fly) | PR |
| Q7L014 | DDX46 | Probable ATP-dependent RNA helicase DDX46 | Homo sapiens (Human) | PR |
| Q569Z5 | Ddx46 | Probable ATP-dependent RNA helicase DDX46 | Mus musculus (Mouse) | PR |
| Q62780 | Ddx46 | Probable ATP-dependent RNA helicase DDX46 | Rattus norvegicus (Rat) | PR |
| Q8H0U8 | RH42 | DEAD-box ATP-dependent RNA helicase 42 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIKISDEKTW | QSSRDSVYEV | GDSYSGQNAN | RPLVATNCSE | YAVAHANCQL | RPVRRFAEVS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LLPDILETMR | NLGLNRLLRL | QSYTWPHLAG | GSGHGAMIVG | SPASGRTFAY | IPPVCHAVSR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ALMDFTGQCE | DVEHDISQPD | RYGPIALILV | PDLRRVHQVS | AMCLALLRKA | HKNDSVTLAL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NVSSTKSSQF | FLKLLNGVGC | LVATPAQLVW | FWQEAPGLMR | FPCLQFLVYD | DVDLMSREQL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QDVQQVLQEI | LPLSHSPQVV | MVSKSYCHTL | MSKLRAVNDK | PALVFGDILE | AALYGGTRIR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ISIMRSEAKA | NAVVQMLQQC | SPEEFRTVIF | CSDDGDMQCL | VAALEVQHYS | CLPYYQTADL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EVRQQVHSWQ | ARSNGVILLC | TDNCPELDIR | DAHTIIHHSM | SHSWSKFKLR | HLKISDNLCN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| MVKPTASIVK | KPLYSLVLLD | DNNHRQLPRL | VDFLQLHQKV | DHRLVEVAKR | IRQELGKARN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DQHQLCDQIL | VLGKCYDPVC | ESRHRLSHID | RRPDYLPASG | DVKVQLVKVY | SPTHFCVRLL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EHLPPKGTWR | MMEYSAVQEF | RMQLTQIKEP | RRYWPPVAGA | ICMYHTTFTK | ERVRVLKVAA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| IKNTNIVQSD | LTVKLQALDV | DTRIFSTNCG | KLFECPEALQ | QEAPLACDLR | LPGWVPYFGE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| RSWTEENIRN | VNLILTQLPK | DHFLQAKILF | VAAGTLFVQD | LVAIMYADQF | KAHVRHLSLA |
| 730 | 740 | 750 | 760 | 770 | 780 |
| RRLVEATLVK | RSENAAEMIR | EFFAEVIIED | DIDENVQDSK | EKANSKPHEK | MKGKMTDQPA |
| 790 | 800 | 810 | 820 | 830 | 840 |
| KLQSQPPLSG | RCLRLANMAH | ESVKENQLHQ | ELQERRYETP | EIPHQSNESD | IPQSNEDRFS |
| 850 | 860 | 870 | 880 | 890 | 900 |
| QLYECIMNCA | SLQLEDESKP | AKHPDHVLSE | SVEFHKIMTN | EDATPDHTQE | KTALLLLPNN |
| 910 | 920 | 930 | 940 | 950 | 960 |
| VARPSVTYYQ | TMTTLEFQVF | LPEDDHDYKA | LLLGAQLFFR | AISKSSDLIL | QFIMTLRFPY |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| SSMSHNIRGR | TVYISVKKLL | ALIDPLAFRE | YRFLKPNHDL | FDKVDKQLQE | TQNRLVRFLE |
| 1030 | 1040 | 1050 | |||
| DMNYVKRNFE | GQEKRETSED | EEVNVEGIER | PDCHKIWDL |