Q9VMQ7
Gene name |
CG6907 |
Protein name |
Elongator complex protein 4 |
Names |
ELP4 |
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG6907 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9VMQ7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9VMQ7-F1 | Predicted | AlphaFoldDB |
No variants for Q9VMQ7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9VMQ7 | |||||
No associated diseases with Q9VMQ7
No regional properties for Q9VMQ7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9VMQ7 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| elongator holoenzyme complex | A heterohexameric protein complex composed two discrete heterotrimeric subcomplexes that is involved in modification of wobble nucleosides in tRNA. |
| transcription elongation factor complex | Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| phosphorylase kinase regulator activity | Modulation of the activity of the enzyme phosphorylase kinase. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| tRNA wobble uridine modification | The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSFRKRTVQ | KPIRGTRTSP | HTAQVITSSG | NPYLDVVIGG | GLPMGSICLI | EEDRFMTHAK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VLAKYFLAEG | VISKQEIFLG | SLDDIPAEML | RRLPRPLTDQ | ESMEQSEVQA | LGDAGAENGL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RIAWRYNDLP | LVNSEHATAK | IGHHFNLMEQ | MDSMMLYNVK | TTLWDDSPKH | LDIVIDEEFS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KSSSPTTPSL | EQQPVEDAPP | IPGTETAPQE | KMPAQEEENS | ANNNNNNNNN | SSSVTSSTKT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GSQDSPLQVF | HNPRYKGLLN | DIQQLLRNES | FVAGTKNNLC | RVCLTSLGSP | LWYDEHFGED |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LIKFLTLLMA | SVRNCNSVCL | ITMPMHLIAK | YDASLVPKIR | QLVDYAIELE | SFAGSERETH |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PAFKEYSGLL | HLHKMSAINT | LAVHMPETPD | LAFKLRRKKF | IIEKFHLPPE | LQESSAKPDN |
| 430 | |||||
| CISGLLSNSN | ATASLDF |