Q9VGP6

PR
Gene name
mgr (CG6719)
Protein name
Prefoldin subunit 3
Names
Protein merry-go-round, von Hippel-Lindau-binding protein 1
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG6719
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-128 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9VGP6

Entry ID Method Resolution Chain Position Source
AF-Q9VGP6-F1 Predicted AlphaFoldDB

No variants for Q9VGP6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9VGP6

No associated diseases with Q9VGP6

No regional properties for Q9VGP6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9VGP6

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
polysome A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
prefoldin complex A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.

2 GO annotations of molecular function

Name Definition
beta-tubulin binding Binding to the microtubule constituent protein beta-tubulin.
tubulin binding Binding to monomeric or multimeric forms of tubulin, including microtubules.

7 GO annotations of biological process

Name Definition
centrosome cycle The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
establishment or maintenance of neuroblast polarity Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.
meiotic spindle assembly The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.
microtubule-based process Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
mitotic spindle assembly Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied.
protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
tubulin complex assembly The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTGIMDSVEM PKLPENQKTF AGIPEAVFLE EIDTFMSQPE NENCEKVLQR LDEQHGKYRF
70 80 90 100 110 120
MACNLEARRR KLKSQIPDLE RSLEMVNVLR KEDEERETQF LLSDQVFIKT LVPPTKTVYL
130 140 150 160 170 180
WLGASVMLEY PLDEAEALLN QNITSAVGNL KSVEHDQDFL RDQITTTEVN MARVYNWGVK
190
KRQAATKTTA TTPS