Q9VG55

PR
Gene name
Hug (CG6371)
Protein name
Protein hugin
Names
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG6371
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

3-126 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9VG55

Entry ID Method Resolution Chain Position Source
AF-Q9VG55-F1 Predicted AlphaFoldDB

No variants for Q9VG55

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9VG55

No associated diseases with Q9VG55

No regional properties for Q9VG55

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9VG55

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

5 GO annotations of molecular function

Name Definition
ecdysis-triggering hormone activity The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system.
hormone activity The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
myostimulatory hormone activity The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction.
neuropeptide receptor binding Binding to a neuropeptide receptor.
signaling receptor binding Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

3 GO annotations of biological process

Name Definition
ecdysis, chitin-based cuticle The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster.
larval feeding behavior Feeding behavior in a larval (immature) organism.
neuropeptide signaling pathway A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MCGPSYCTLL LIAASCYILV CSHAKSLQGT SKLDLGNHIS AGSARGSLSP ASPALSEARQ
70 80 90 100 110 120
KRAMGDYKEL TDIIDELEEN SLAQKASATM QVAAMPPQGQ EFDLDTMPPL TYYLLLQKLR
130 140 150 160 170 180
QLQSNGEPAY RVRTPRLGRS IDSWRLLDAE GATGMAGGEE AIGGQFMQRM VKKSVPFKPR
190
LGKRAQVCGG D