Q9VFB7

PR
Gene name
SIDL (CG6623)
Protein name
Trafficking protein particle complex subunit 10
Names
Shal Interactor of Di-Leucine Motif, Trafficking protein particle complex subunit TMEM1, Transport protein particle subunit TMEM1, TRAPP subunit TMEM1
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG6623
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

367-475 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9VFB7

Entry ID Method Resolution Chain Position Source
AF-Q9VFB7-F1 Predicted AlphaFoldDB

No variants for Q9VFB7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9VFB7

No associated diseases with Q9VFB7

6 regional properties for Q9VFB7

Type Name Position InterPro Accession
domain TRAM domain 390 - 461 IPR002792
domain Elp3/MiaA/NifB-like, radical SAM core domain 162 - 379 IPR006638
domain Radical SAM 158 - 387 IPR007197
domain Methylthiotransferase, N-terminal 19 - 135 IPR013848
conserved_site Methylthiotransferase, conserved site 166 - 186 IPR020612
domain RimO, TRAM domain 393 - 459 IPR041582

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus, cis-Golgi network
  • Cell projection, dendrite
  • Perikaryon
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
dendrite A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
perikaryon The portion of the cell soma (neuronal cell body) that excludes the nucleus.
TRAPP complex A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active.
TRAPPII protein complex A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the phagophore assembly site. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs65, Trs120, Trs130. The whole complex is thought to dimerize with itself.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

4 GO annotations of biological process

Name Definition
early endosome to Golgi transport The directed movement of substances from early endosomes to the Golgi.
Golgi vesicle transport The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
intra-Golgi vesicle-mediated transport The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).
regulation of GTPase activity Any process that modulates the rate of GTP hydrolysis by a GTPase.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQIKPIITYS GSCPLFRSLE SQILNAIPLD TCEWRRTFQR PTKHVRLEAQ AQQFNVAALE
70 80 90 100 110 120
KYKQGDWSIL EHPILHIFVT ECNDVDTYKA TIREAIDIWL KTLTSYGVSD WMILLVETLD
130 140 150 160 170 180
MRKTKNFMPR TTVLDKIRLD FGTKNDDRCI SVLNPAKFEQ KSTESFRCLV QRIRFLMLTS
190 200 210 220 230 240
YNRNIVKYEE LIRSKREKRN IEGWDFRQYF FMQEDLALIF EKLELPTEAL IQYDELDAMF
250 260 270 280 290 300
SQFITHTGLN EKQQWLNHFR KPLDAFHGIC LTRADKFEMR NKIRDEGVSL LEFRNYLFER
310 320 330 340 350 360
QAYLLLTCND IPEIAKRLLN FLFSTLREVE LIKLECQEGA LCCWEFVCAL EVLQLCEQAM
370 380 390 400 410 420
EPNELTCFQH CAPIWNLAKD KLYELGKLCG LLPGCTPTSE QLHIVVQLSS GIGDAPSEQH
430 440 450 460 470 480
QFLQATPQLR DRSPNRKPKK SGAEQLKEAL GSNQAFQKLY LELAELAIST YKHVTRLRSA
490 500 510 520 530 540
RLVGLDLGNF YCALNEPHKA VGFFTDLLRE LKAENWHMLS SQTLLELANC YRKMGDSLAY
550 560 570 580 590 600
TKTCSSISCC AELETLVRTF YFDEFLKSLK TLKTTLSAQP SIENANYCVL EDHFRILDIE
610 620 630 640 650 660
VVNQKPIIQD DYILVQLKVE SLYPRGVVAE NVKLCYELEA SSLELAMENV SLTASPSTVK
670 680 690 700 710 720
AKDTSSRLKV SLQLVYKQDN RLHSAAVACD LPKSKQPVRR TSSTKRKLSP SVQADFTNFV
730 740 750 760 770 780
QAENIALQPG VNLIEMKAKA TRVGCWQFKQ LCISMSSLEF LSEQLPFMPA TFEISTKPAS
790 800 810 820 830 840
ATLEFKTLIA GIVQPISLNV SGGSFIFPPD AKITLRCSKN LRIRQARNTD DEAAYNDDQS
850 860 870 880 890 900
FESTLQVPLV QFKSFEERRI PLEVLTDMPG RKVSKHHEHH IALNCPWSRT ELPIAVDFQP
910 920 930 940 950 960
AMEATCRLHT CGTQKFLQVI MKGMEAHLLL QHAQVKCDVP GVQLLDLNPE SQQPIEIYKS
970 980 990 1000 1010 1020
LTVTYLYEIQ VEPLKTEHEL PVVKVHFVIK YASLSQPDVW RTYGCAFDLV DYTTLFKLQA
1030 1040 1050 1060 1070 1080
QLEPNELCRL RTVCNMNLKI TKVHENPYTD LMYEVLNDQN LWAVCGRSAG VVSMKDVDSH
1090 1100 1110 1120 1130 1140
SISLDVMPLS TGFLPMPSIR LSKYTAGGKS KTDGHSKVHP FPPGQVYNST KSMQIHVIAS
VAGDQ