Q9VCB1
Gene name |
CG13609 |
Protein name |
Protein PTOV1 homolog |
Names |
|
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG13609 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9VCB1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9VCB1-F1 | Predicted | AlphaFoldDB |
No variants for Q9VCB1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9VCB1 | |||||
No associated diseases with Q9VCB1
No regional properties for Q9VCB1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9VCB1 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| mediator complex | A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. |
| transcription regulator complex | A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| positive regulation of transcription by RNA polymerase II | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q86YD1 | PTOV1 | Prostate tumor-overexpressed gene 1 protein | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEPVPEEARG | VGDDEGELDC | LTHMIGALLL | QKEPENPENG | DSKETIWSGE | LEWEDAQILD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QPKTLHTVQC | KICSMVKEGQ | PEINTENWPN | KLKTQLIPKK | VLGKIGEQFL | KDARMVVFRS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SQGEVLNLLI | TAMSSGFAGC | IHFPSNPNCN | IKALILIYSR | DHQALVGFIP | NNEDSFSERL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QEILQGAKRK | PGVKTPKQPQ | PEEPPPVEED | AIINELLWTG | SLNWSTQASL | EEPSISHKLE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CSVYIAIKNG | DPGISAEDWP | TDMPMVLMPS | IYLGQFAGAF | IKDSKLIILR | STPGEEHDSL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ASSMSAGSCG | CARFSSEVVC | KVIMLLYSSP | RNAFLGFIPR | DQANFVKRLR | EVLDEHRQKA |
| RNKE |