Q9V5L3

PR
Gene name
Cyp49a1 (CG18377)
Protein name
Probable cytochrome P450 49a1
Names
CYPXLIXA1
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG18377
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-99 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9V5L3

Entry ID Method Resolution Chain Position Source
AF-Q9V5L3-F1 Predicted AlphaFoldDB

No variants for Q9V5L3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9V5L3

No associated diseases with Q9V5L3

1 regional properties for Q9V5L3

Type Name Position InterPro Accession
conserved_site Cytochrome P450, conserved site 529 - 538 IPR017972

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Peripheral membrane protein
  • Microsome membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.

4 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9VYQ5 Cyp318a1 Probable cytochrome P450 318a1 Drosophila melanogaster (Fruit fly) PR
10 20 30 40 50 60
MSGLRKTSIA LMRRSTSSTT ILPHSGGVGG AVSPPSSGVG VATEIEKSIA MQRLRTGESS
70 80 90 100 110 120
NPKKLNVSQQ PVTSVATTRT TASSLPAETT SSPAAAVRPY SEVPGPYPLP LIGNSWRFAP
130 140 150 160 170 180
LIGTYKISDL DKVMNELHVN YGKMAKVGGL IGHPDLLFVF DGDEIRNIFK KEEAMPHRPS
190 200 210 220 230 240
MPSLRHYKGD LRRDFFGDVA GLIGVHGPKW EAFRQEVQHI LLQPQTAKKY IPPLNDIASE
250 260 270 280 290 300
FMGRIELMRD EKDELPANFL HELYKWALES VGRVSLDTRL GCLSPEGSEE AQQIIEAINT
310 320 330 340 350 360
FFWAVPELEL RMPLWRIYPT KAYRSFVKAL DQFTAICMKN IGKTMDKADA DEARGLSKSE
370 380 390 400 410 420
ADISIVERIV RKTGNRKLAA ILALDLFLVG VDTTSVAASS TIYQLAKNPD KQKKLFDELQ
430 440 450 460 470 480
KVFPHREADI NQNVLEQMPY LRACVKETLR MRPVVIANGR SLQSDAVING YHVPKGTHVI
490 500 510 520 530 540
FPHLVVSNDP AYFPEPKRFL PERWLKQSTD AAGCPHANQK IHPFVSLPFG FGRRMCVGRR
550 560 570 580
FAEIELHTLL AKIFRKYKVS YNSGEFVYRV NSTYIPQSPL NFKLTLRDE