Q9V122

PR
Gene name
psmA
Protein name
Proteasome subunit alpha
Names
20S proteasome alpha subunit, Proteasome core protein PsmA
Species
Pyrococcus abyssi (strain GE5 / Orsay)
KEGG Pathway
pab:PAB0417
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

207-260 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9V122

Entry ID Method Resolution Chain Position Source
AF-Q9V122-F1 Predicted AlphaFoldDB

No variants for Q9V122

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9V122

No associated diseases with Q9V122

1 regional properties for Q9V122

Type Name Position InterPro Accession
domain Proteasome alpha-subunit, N-terminal domain 10 - 32 IPR000426

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
proteasome core complex, alpha-subunit complex The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.

1 GO annotations of molecular function

Name Definition
threonine-type endopeptidase activity Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.

2 GO annotations of biological process

Name Definition
proteasomal protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFVPPQAGY DRAITVFSPD GRLFQVNYAR EAVKRGATAV GVKCKDGVVL AVEKRITSRL
70 80 90 100 110 120
IEPESYEKIF QIDDHIAAAS SGIIADARVL VNRARLEAQI HRLTYGEPAP LAVIVKKICD
130 140 150 160 170 180
LKQMHTQYGG VRPFGAALLM AGVNDKPELY ETDPSGAYFA WKAVAIGSGR NTAMAIFEDK
190 200 210 220 230 240
YRDDMTLDEA IKLAIFALAK TMEKPSAENI EVAVITVKDK KFRKLSKEEI EKFLGEVMKE
250
VEEEEVKEKE EDYSELDSHY