Q9UZW0
Gene name |
pgk (PYRAB10360, PAB1679) |
Protein name |
Phosphoglycerate kinase |
Names |
|
Species |
Pyrococcus abyssi (strain GE5 / Orsay) |
KEGG Pathway |
pab:PAB1679 |
EC number |
2.7.2.3: Phosphotransferases with a carboxy group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9UZW0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9UZW0-F1 | Predicted | AlphaFoldDB |
No variants for Q9UZW0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9UZW0 | |||||
No associated diseases with Q9UZW0
4 regional properties for Q9UZW0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Phosphoglucose isomerase, conserved site | 195 - 208 | IPR018189-1 |
| conserved_site | Phosphoglucose isomerase, conserved site | 403 - 420 | IPR018189-2 |
| domain | Phosphoglucose isomerase, SIS domain 1 | 84 - 215 | IPR035476 |
| domain | Phosphoglucose isomerase, SIS domain 2 | 261 - 424 | IPR035482 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.2.3 | Phosphotransferases with a carboxy group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| phosphoglycerate kinase activity | Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H(+). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glycolytic process | The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFRLGDFNYH | NKVVFLRVDL | NSPMKDGKII | SDARFRAVLP | TIKYLLENGA | RVVVGTHQGK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PYSEDYATTE | EHARILSNLL | NQHVEYVEDI | FGRYAREKIQ | ELKPGEIAML | ENLRFSAEEV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KNKPIEECEK | TFFVKKLSKV | IDYVVNDAFA | AAHRSQPSLV | GFARIKPMIM | GFLMEREIEA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LMKAYYSKES | PRVYVLGGAK | VDDSLKVAEN | VLRRGFADVI | LTGGLVANVF | TLAKGFDLGR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KNIEFMKKKG | LLELVKHAEK | ILDEFYPYVR | TPVDFAIDYK | GDREEIYLLS | EKRELLNDYQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IMDIGSRTIE | KYRDIIMKAK | VVVANGPMGV | FEREEFALGT | VEVFKAIAES | EAFSVLGGGH |
| 370 | 380 | 390 | 400 | ||
| SIASIQKYGI | EGITHISTGG | GAMLTFFAGE | ELPVLRALQI | SYEKFKEVKA |