Q9UZP4
Gene name |
rnz |
Protein name |
Ribonuclease Z |
Names |
RNase Z, tRNA 3 endonuclease, tRNase Z |
Species |
Pyrococcus abyssi (strain GE5 / Orsay) |
KEGG Pathway |
pab:PAB0728 |
EC number |
3.1.26.11: Endoribonucleases producing 5'-phosphomonoesters |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9UZP4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9UZP4-F1 | Predicted | AlphaFoldDB |
No variants for Q9UZP4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9UZP4 | |||||
No associated diseases with Q9UZP4
1 regional properties for Q9UZP4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | DNA-directed RNA polymerase, 14-18kDa subunit, conserved site | 76 - 90 | IPR020708 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.26.11 | Endoribonucleases producing 5'-phosphomonoesters |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 3'-tRNA processing endoribonuclease activity | Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule. |
| zinc ion binding | Binding to a zinc ion (Zn). |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIEVIFLGTG | GIKPTPERNV | PSIAIKVEGE | LILFDVGEGT | LRQMEIAGLS | PMKIRRIFIT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HFHGDHYLGL | PALIQTMNLW | KRKEPLHIYG | PENSIEFIKN | LLNSGYFAPS | FDVTVHELPG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KARLQFEKYE | VWAFEVSHGV | PALGYVFKEK | DRRGSFDLEK | IKNLGLEPGP | WMKELEEKKV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| INIGGRTIRL | SEVTGPKKRG | AKIVYTGDTE | PCENVIQFSR | RANLLIHEAT | YLNSEDRGES |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YHTTVEEACE | IWKKSKAFNL | ALFHRGPRYS | FKEYKEGATK | LCPQAMIPRD | FDRIMVKGAE |
| YVIFKVR |