Q9UYQ9

PR
Gene name
pcp (PYRAB14480, PAB1419)
Protein name
Pyrrolidone-carboxylate peptidase
Names
5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase
Species
Pyrococcus abyssi (strain GE5 / Orsay)
KEGG Pathway
pab:PAB1419
EC number
3.4.19.3: Omega peptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

145-200 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9UYQ9

Entry ID Method Resolution Chain Position Source
AF-Q9UYQ9-F1 Predicted AlphaFoldDB

No variants for Q9UYQ9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9UYQ9

No associated diseases with Q9UYQ9

2 regional properties for Q9UYQ9

Type Name Position InterPro Accession
active_site Pyroglutamyl peptidase I, Glu active site 68 - 84 IPR033693
active_site Pyroglutamyl peptidase I, Cys active site 129 - 143 IPR033694

Functions

Description
EC Number 3.4.19.3 Omega peptidases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

1 GO annotations of molecular function

Name Definition
pyroglutamyl-peptidase activity Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKVLVTGFEP FGGDDKNPTM EIVKFLDGKE IGGAKVIGRV LPVSFKRARK ELVAILDEIK
70 80 90 100 110 120
PDVTINLGLA PGRTHISVER VAVNIIDARI PDNDGEKPID EPIVENGPAA YFATIPTREI
130 140 150 160 170 180
VEEMKRNNIP AVLSYTAGTY LCNFVMYLTL HHSATKGYPR KAGFIHVPYT PDQVIEKKNT
190
PSMSLELEIK GVEIAIRKSL