Q9UX16

PR
Gene name
taw3
Protein name
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase
Names
tRNA wyosine derivatives biosynthesis protein Taw3
Species
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
KEGG Pathway
sso:SSO0622
EC number
2.1.1.282: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

151-209 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for Q9UX16

Entry ID Method Resolution Chain Position Source
1TLJ X-ray 280 A A/B 1-209 PDB
AF-Q9UX16-F1 Predicted AlphaFoldDB

No variants for Q9UX16

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9UX16

No associated diseases with Q9UX16

5 regional properties for Q9UX16

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 2 - 241 IPR003439
domain AAA+ ATPase domain 30 - 218 IPR003593
conserved_site ABC transporter-like, conserved site 141 - 155 IPR017871
domain NIL domain 265 - 340 IPR018449
domain Methionine import ATP-binding protein MetN, ATP-binding domain 1 - 233 IPR041701

Functions

Description
EC Number 2.1.1.282 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
tRNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule.

2 GO annotations of biological process

Name Definition
tRNA methylation The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
wybutosine biosynthetic process The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazopurine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLVWEELREK ALNKIYHDKE IGYLDPDILG FLLAFYRNRN DVYTQSSCSG RITIVDAEMP
70 80 90 100 110 120
WDRKNSTIIF KNHLRITEQD LEDVLSKNQV RRLWLIVQGP IIHIYAKNIE TGWDILKIAR
130 140 150 160 170 180
EAGFKHSGIL ATNQKGVLVE LRTGIRMVHL LRESNTERVD KDKIKTLVNV CNEVLARGKQ
190 200
KMNLLKDLLS SSSNNSMELG KNSKLKTPI