Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9UW25

Entry ID Method Resolution Chain Position Source
AF-Q9UW25-F1 Predicted AlphaFoldDB

No variants for Q9UW25

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9UW25

No associated diseases with Q9UW25

1 regional properties for Q9UW25

Type Name Position InterPro Accession
domain Ovate protein family, C-terminal 284 - 345 IPR006458

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cortical endoplasmic reticulum A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

2 GO annotations of molecular function

Name Definition
sterol binding Binding to a sterol, a steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol.
sterol transporter activity Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

5 GO annotations of biological process

Name Definition
endocytosis A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
exocytosis A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
maintenance of cell polarity The maintenance of established anisotropic intracellular organization or cell growth patterns.
piecemeal microautophagy of the nucleus Degradation of a cell nucleus by lysosomal microautophagy.
single-species biofilm formation on inanimate substrate A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGLTSKLEKL KLKELTGHEA AVKSNVVNGA DTDDTDDIDE MDNEGQSILM GIIAQLRPGM
70 80 90 100 110 120
DLSRITLPTF ILEKKSMLER ITNFFQIPDM LLKANRTSDD VERFVSVLAW YLASWHIAPK
130 140 150 160 170 180
AVKKPLNPVL GETFNCYWEN ISDDCSAYYI SEQVSHHPPK SSYFYLVPEA KIKVDGILIP
190 200 210 220 230 240
KSRFLGNSSA AMMEGWAHLT LGEHENEVYE MNQPNVYCRG ILFGKMKMEL GDHMYVKCRK
250 260 270 280 290 300
TGLEADIDFK TKGFISGTYD AIEGVIKNSK TSEVLYQITG KWNEVMEIKD LKTGKKRVLV
310 320 330 340 350 360
DTKSSVPVKP RVRPLEEQGQ YESRKLWKPT IDALARRDHT VATEEKFAVE DEQRNLAKKR
370 380 390 400 410 420
IDDGVEFHPK FFRPVNEKEV ELQDLEYVIY KKFDLKSNPE VLTDEVLSIA PILPGQKHDE
430
KFEIPAFKKH EET