Q9UUJ6

PR
Gene name
ned1 (SPAC1952.13)
Protein name
Nuclear elongation and deformation protein 1
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC1952.13
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

65-235 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9UUJ6

Entry ID Method Resolution Chain Position Source
AF-Q9UUJ6-F1 Predicted AlphaFoldDB

6 variants for Q9UUJ6

Variant ID(s) Position Change Description Diseaes Association Provenance
I_4991327_A_G 38 T>A No Jeffares_SNPs
I_4992235_C_T 291 P>L No Jeffares_SNPs
I_4992253_C_T 297 S>F No Jeffares_SNPs
I_4992814_G_T 484 C>F No Jeffares_SNPs
I_4993114_T_C 584 L>P No Jeffares_SNPs
I_4993297_A_G 645 D>G No Jeffares_SNPs

No associated diseases with Q9UUJ6

3 regional properties for Q9UUJ6

Type Name Position InterPro Accession
domain Lipin, N-terminal 1 - 100 IPR007651
domain Lipin/Ned1/Smp2 (LNS2) 334 - 560 IPR013209
domain LNS2/PITP 379 - 537 IPR031315

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
phosphatidate phosphatase activity Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.

6 GO annotations of biological process

Name Definition
cellular lipid metabolic process The chemical reactions and pathways involving lipids, as carried out by individual cells.
endoplasmic reticulum organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
lipid storage The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
nuclear membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane.
triglyceride biosynthetic process The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQYVGRAFDS VTKTWNAINP STLSGAIDVI VVEQEDKTLA CSPFHVRFGK FSLLLPSDKK
70 80 90 100 110 120
VEFSVNGQLT GFNMKLGDGG EAFFVFATEN AVPRELQTSP IVSPTTSPKQ TPSINVTEPQ
130 140 150 160 170 180
DLELDKVSQD HEKDQSNTYL MEDGYEFPLT RDLIRRSKSD ADQTPPTGFK HLRHSSCLEM
190 200 210 220 230 240
AGSDRTPSMP ATTLADLRLL QKAKELGKRL SGKELPTRVG DNGDVMLDMT GYKSSAANIN
250 260 270 280 290 300
IAELARETFK DEFPMIEKLL REDEEGNLWF HASEDAKKFA EVYGHSPPAS PSRTPASPKS
310 320 330 340 350 360
DSALMDEDSD LSRRHSLSEQ SLSPVSESYP QYAKTLRLTS DQLRSLNLKP GKNELSFGVN
370 380 390 400 410 420
GGKAICTANL FFWKHNDPVV ISDIDGTITK SDALGHMFTL IGKDWTHAGV AKLYTDITNN
430 440 450 460 470 480
GYKIMYLTSR SVGQADSTRH YLRNIEQNGY SLPDGPVILS PDRTMAALHR EVILRKPEVF
490 500 510 520 530 540
KMACLRDLCN IFALPVPRTP FYAGFGNRIT DAISYNHVRV PPTRIFTINS AGEVHIELLQ
550 560 570 580 590 600
RSGHRSSYVY MNELVDHFFP PIEVSTRDEV SSFTDVNFWR SPLLELSDEE EDDTNKSTSK
610 620 630 640 650
SPKTPKNTKF GYQEFEGIDE EDAQDYSPSP LIKSFNELMF EGEEDEEGEE DVENAV