Q9UUH3
Gene name |
mug58 (SPAC630.09c) |
Protein name |
Uncharacterized kinase mug58 |
Names |
Meiotically up-regulated gene 58 protein |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC630.09c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9UUH3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9UUH3-F1 | Predicted | AlphaFoldDB |
5 variants for Q9UUH3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_363588_T_A | 5 | E>D | No | Jeffares_SNPs | |
| I_363302_C_T | 101 | V>I | No | Jeffares_SNPs | |
| I_363232_C_T | 124 | G>D | No | Jeffares_SNPs | |
| I_363137_C_T | 156 | E>K | No | Jeffares_SNPs | |
| I_363014_C_T | 197 | D>N | No | Jeffares_SNPs |
No associated diseases with Q9UUH3
1 regional properties for Q9UUH3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zeta toxin domain | 16 - 79 | IPR010488 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| glycerate kinase activity | Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H(+). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| meiotic cell cycle | Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSLEIIVDK | ILKFLEKQPK | PEGRPFILGI | SGPQGSGKST | LASALDTELT | RKNESVVKFS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LDDFYLTHAE | QVELAKNNPN | NPLVQHRGLA | GTHDVTFLNN | VLNAFVKGSD | EEVSIPFYDK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SKFGGYGDRG | DESQWKKANP | KTTTYVIFEG | WMVGFEPLDS | CMLSVRARST | RWQNIEGSLL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WVNRKLADYQ | PIFQKIDSLV | ELEAQEINYV | YRWRLQQEHA | LKARIHKGMS | DEEVIEFVNH |
| 250 | 260 | 270 | |||
| YMPQYVFYLG | TLSNKVHLNP | HCLEIILDEN | RYPVVMH |