Q9UUA1
Gene name |
SPCC23B6.01c |
Protein name |
Oxysterol-binding protein homolog C23B6.01c |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPCC23B6.01c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9UUA1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9UUA1-F1 | Predicted | AlphaFoldDB |
No variants for Q9UUA1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9UUA1 | |||||
No associated diseases with Q9UUA1
1 regional properties for Q9UUA1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Peptide methionine sulphoxide reductase MrsB domain | 7 - 134 | IPR002579 |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cortical endoplasmic reticulum | A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| intracellular membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| oxysterol binding | Binding to oxysterol, an oxidized form of cholesterol. |
| sterol binding | Binding to a sterol, a steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol. |
| sterol transfer activity | Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. |
| sterol transporter activity | Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| endocytosis | A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. |
| exocytosis | A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. |
| maintenance of cell polarity | The maintenance of established anisotropic intracellular organization or cell growth patterns. |
| piecemeal microautophagy of the nucleus | Degradation of a cell nucleus by lysosomal microautophagy. |
| sterol transport | The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPHEKQDRDA | EEIEDEGKNI | ILGIVSQLRP | NMDLSKVTFP | TFVLEPKSML | ERITNFMSHP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DLLLNVQKTA | DPEMRFLDVV | RFYMSGWHIR | PRGVKKPLNP | ILGETFTGFW | KFPPSNSKDP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NLQKLHGIAV | YAAEQVCHHP | PISAYFYLCP | EYKVRIDGVV | KPRSRFLGNS | AASIMEGIAS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IKLQDLDEEY | LITQPNVYAR | GILFGKMRLE | LGDHVTVRCP | KTDLQADIEF | KVKGFISGTY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NSIAGKVKRV | STGEVLYKIS | GKWDSEMSVE | SVKTGETRPL | LDVSKHDVYL | VSARPLEEQG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ERESQRLWYK | TCQAVIARDQ | TTATETKSAI | EDRQREEAKQ | REIENVQWKP | KYFKMIAPEE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YILNFDIPNG | KSDLEVLCAL | DEFIPIFSEV | DRIAFHKFLS | ENTKPEDSSI | HKHSRDASGD |
| 430 | 440 | 450 | 460 | 470 | |
| STKGFAEHMP | APARRRRPQS | TASFVTYRSD | NGSVDEYHDA | QLPDPNTLSK | LHEEQDPAL |