Q9UTF8
Gene name |
ugo1 (SPAC1B2.02c) |
Protein name |
Mitochondrial fusion and transport protein ugo1 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC1B2.02c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9UTF8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9UTF8-F1 | Predicted | AlphaFoldDB |
2 variants for Q9UTF8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_2809552_G_A | 86 | P>S | No | Jeffares_SNPs | |
| I_2809470_G_C | 113 | T>R | No | Jeffares_SNPs |
No associated diseases with Q9UTF8
2 regional properties for Q9UTF8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Mitochondrial substrate/solute carrier | 42 - 195 | IPR018108-1 |
| repeat | Mitochondrial substrate/solute carrier | 318 - 419 | IPR018108-2 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of mitochondrial inner membrane | The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial outer membrane | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| thiamine transmembrane transporter activity | Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial fusion | Merging of two or more mitochondria within a cell to form a single compartment. |
| thiamine pyrophosphate transmembrane transport | The process in which thiamine pyrophosphate is transported across a membrane. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNPYRPYVVV | NNVEPTFSIT | PEPTFETQPT | ISKSEIFETL | RSILVTKYLT | TFFVQPLEVA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KTVCQVEEYL | PKRTKIERDG | KQTKEPYDED | IPDGTEQEGL | SDDEHEIYAY | FETPTTEKAV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TEQLAEKLCV | DASGYVTDPS | NLIERSYTIH | SKRFSIKSII | SELWEKEGAR | GLWKGHTISF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LHNLLYSGLQ | SWLSATLSGA | LAIADPNIIS | PIDSVRPLLS | LFIKSITSAI | SALILSPLDI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ARTKIILFPI | SSSSYLSSAS | ETSGNSHKKF | KPLTIRQCLK | ALPFYCPSSL | ILPTVCYVSL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PPFVSSVLPL | TFRNFLGSSP | TLDAMVGLGT | SAVQFLLKCP | LEMVLRRAQA | QYECNLPPQT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IVPVGKYTGI | VGTIWCLLSE | EDPGKFGIEG | LYRGWRVGIW | GMSSTLALNY | ISSNLREEVE |
| F |