Q9USW9
Gene name |
sgf29 (SPBC1921.07c, SPBC21D10.13) |
Protein name |
SAGA-associated factor 29 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC1921.07c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9USW9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9USW9-F1 | Predicted | AlphaFoldDB |
No variants for Q9USW9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9USW9 | |||||
No associated diseases with Q9USW9
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| SAGA complex | A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695). |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| methylated histone binding | Binding to a histone in which a residue has been modified by methylation. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| histone acetylation | The modification of a histone by the addition of an acetyl group. |
| histone H3 acetylation | The modification of histone H3 by the addition of an acetyl group. |
| positive regulation of DNA-templated transcription | Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVRPINAEED | VTSMWVKFHE | SLNPIRSSLI | KQEECYKTVD | GDDNPIEERI | KACDAGIQTS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EEQKKELEHT | MQSLEMIINV | LEKANEKPVI | TNSPLTRSRR | NRGTSFTANT | VTFTPGMSVA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FKLPYTRHNE | GGDWIQCIII | KVTGEGAKQR | FEVQDPEPDD | DGNAGQIYKT | TANHLIQIPA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KGTPLPPISP | KTNVLARYPE | TTTFYRAEVI | RTLPDGSCKL | RFEGEEEVGK | ETVVERHLVL |
| EYNG |