Q9UST1
Gene name |
ppk26 (pan3) |
Protein name |
PAN2-PAN3 deadenylation complex subunit pan3 |
Names |
PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 3, PAN deadenylation complex subunit 3 |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC336.14c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9UST1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9UST1-F1 | Predicted | AlphaFoldDB |
No variants for Q9UST1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9UST1 | |||||
No associated diseases with Q9UST1
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| P-body | A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing. |
| PAN complex | A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| metal ion binding | Binding to a metal ion. |
| poly(A) binding | Binding to a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA. |
| protein kinase activity | Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA processing | Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. |
| nuclear-transcribed mRNA poly(A) tail shortening | Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length. |
| protein phosphorylation | The process of introducing a phosphate group on to a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSVRKNSPAS | PKPTSRSRES | SRSPSVTDLK | DHSKAKRTLC | RNILLYGSCK | HSENGCAFRH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DGPFIPSSEN | LEQYSVKKKL | NAASASFQPV | RALPVKAAGA | AVFVPKSQEK | SLFLSRERTP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VALSPGSHAI | NPYNNASMLV | NEPFHDDSGV | YYTRQNQFKP | TLYNLYNPQP | SPMPTLLPYE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RTVNGLFIDD | TTRERIERKS | EASRQTISAL | PSIISSYTSL | APLNTKLYRY | KEQIGFSSWT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YKCTSSIDGN | AYVLKRLQDC | SINIDTSTVD | KLKNVFHPNI | VPFHSAFHTD | TFHDSSLLLI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YDFYPCTTTL | GELYLNNSKN | SVKLEENRKI | PERELWNYFF | QLTIALSYLH | KSGFACNKLT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PSRILVDQTE | RIRISGCADY | ELVVSNKPPL | EERKKQDFVD | LGVVIANLAT | GRTDMDMSSA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ARAIYSTYSR | EFYKAVLYFV | SEVPEDKNLE | LFLQNHIESF | FPIMSSPYVE | CEKMERKISD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AFQHGRFFNI | LCKIMFIIDN | NRASREYPIA | REKEISLIYL | LRDYLFHQID | EDECPVIDLY |
| 550 | 560 | 570 | 580 | ||
| QVLNRLGKLD | AGINQAIALI | SRDELDCVSV | SYGELKAWLD | NVYEMEINS |