Q9USR2
Gene name |
ubp10 (SPBC577.07) |
Protein name |
Probable mRNA-splicing protein ubp10 |
Names |
Probable inactive ubiquitin-specific-processing protease 10 |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC577.07 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9USR2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9USR2-F1 | Predicted | AlphaFoldDB |
No variants for Q9USR2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9USR2 | |||||
No associated diseases with Q9USR2
1 regional properties for Q9USR2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Glycerophosphodiester phosphodiesterase domain | 7 - 244 | IPR030395 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| spliceosomal complex | Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA. |
| U4/U6 x U5 tri-snRNP complex | A ribonucleoprotein complex that is formed by the association of the U4/U6 and U5 snRNPs. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| cysteine-type deubiquitinase activity | An thiol-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated. |
| zinc ion binding | Binding to a zinc ion (Zn). |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA cis splicing, via spliceosome | The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript. |
| protein deubiquitination | The removal of one or more ubiquitin groups from a protein. |
| protein modification by small protein conjugation or removal | A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein. |
| spliceosomal complex assembly | The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSENKDKNNI | LKRHIEEDNN | IDNGKRKKLE | LGKDMEDVHD | IASKEMEEHE | TTPIISQNLY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LDTINRKLLD | FDFEKVCSVS | LTNLSVYACL | VCGRYFQGRG | PSSHAYFHAL | TENHHVFVNC |
| 130 | 140 | 150 | 160 | 170 | 180 |
| STLKFYVLPE | SYQVESSALQ | DIAYVMRPTF | TKLEVQRLDH | TPQLSYDLML | KPYVPGFVGM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NNIKNNDYFN | VVIHMLAHVK | PFRNYFLLKN | FDNCPQLVQR | LAILIRKLWN | HKAFKSHVSP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QELIQEVTVL | SHKKYSINEQ | KDPVEFLSWF | LNTLHNCLGG | KKSTIAKPTS | IVHYSFQGFV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RIESQKIRQH | AEKGEQVVFT | GDRVIQTNVV | PFLYLTLDLP | PKPIFQDEFE | GNIIPQVELK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EILNKYNGVH | TQELAGMRRR | FHLMTAPPYF | IFHIKRFMKN | NYFTERNQTI | VTFPLDDFDM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SPFIDDSFIQ | SNPKISTKYN | LVANIIHESV | THAEEEFHNF | RIQIRNPSTN | KWYQIQDLYV |
| 490 | 500 | ||||
| EEISSDMIRL | GESFIQLWER | SS |