Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9US40
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9US40-F1 | Predicted | AlphaFoldDB |
36 variants for Q9US40
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_5445353_T_G | 2 | S>A | No | Jeffares_SNPs | |
| I_5445378_T_G | 10 | V>G | No | Jeffares_SNPs | |
| I_5445381_C_A | 11 | S>Y | No | Jeffares_SNPs | |
| I_5445437_G_A | 30 | A>T | No | Jeffares_SNPs | |
| I_5445475_T_A | 42 | D>E | No | Jeffares_SNPs | |
| I_5445485_A_G | 46 | I>V | No | Jeffares_SNPs | |
| I_5445511_G_T | 54 | E>D | No | Jeffares_SNPs | |
| I_5445615_T_G | 89 | V>G | No | Jeffares_SNPs | |
| I_5445617_T_C | 90 | F>L | No | Jeffares_SNPs | |
| I_5445692_T_G | 115 | S>A | No | Jeffares_SNPs | |
| I_5445885_C_T | 179 | T>I | No | Jeffares_SNPs | |
| I_5445888_T_C | 180 | V>A | No | Jeffares_SNPs | |
| I_5445887_G_A | 180 | V>I | No | Jeffares_SNPs | |
| I_5446034_C_T | 229 | L>F | No | Jeffares_SNPs | |
| I_5446052_A_G | 235 | T>A | No | Jeffares_SNPs | |
| I_5446076_A_G | 243 | N>D | No | Jeffares_SNPs | |
| I_5446114_T_A | 255 | D>E | No | Jeffares_SNPs | |
| I_5446142_G_A | 265 | G>S | No | Jeffares_SNPs | |
| I_5446238_G_T | 297 | V>F | No | Jeffares_SNPs | |
| I_5446337_T_G | 330 | S>A | No | Jeffares_SNPs | |
| I_5446386_C_T | 346 | A>V | No | Jeffares_SNPs | |
| I_5446708_T_A | 453 | F>L | No | Jeffares_SNPs | |
| I_5446713_A_G | 455 | K>R | No | Jeffares_SNPs | |
| I_5446718_G_T | 457 | A>S | No | Jeffares_SNPs | |
| I_5446777_G_C | 476 | L>F | No | Jeffares_SNPs | |
| I_5446784_T_G | 479 | S>A | No | Jeffares_SNPs | |
| I_5446841_G_C | 498 | A>P | No | Jeffares_SNPs | |
| I_5446997_G_T | 550 | V>L | No | Jeffares_SNPs | |
| I_5447001_A_C | 551 | Q>P | No | Jeffares_SNPs | |
| I_5447007_A_G | 553 | D>G | No | Jeffares_SNPs | |
| I_5447006_G_T | 553 | D>Y | No | Jeffares_SNPs | |
| I_5447025_A_C | 559 | D>A | No | Jeffares_SNPs | |
| I_5447027_C_G | 560 | Q>E | No | Jeffares_SNPs | |
| I_5447030_C_T | 561 | L>F | No | Jeffares_SNPs | |
| I_5447043_G_A | 565 | G>E | No | Jeffares_SNPs | |
| I_5447048_C_A | 567 | L>I | No | Jeffares_SNPs |
No associated diseases with Q9US40
No regional properties for Q9US40
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9US40 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| amino acid transmembrane transporter activity | Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSIMEKTDV | SSSKHSFTFE | PSSDEVGKAA | EIVDTHENFY | DDQGDIDNPE | ELAELGYKQE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FRRQLSLFGI | FSISFSVLGM | LPSVASTLVF | GLWYVGYPGL | LWAWLIAMFF | LICVSMSMAE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ICSAMPTSGG | LYYAAAVFAP | KGWGPLASWI | TGWSNYIGNI | IGQPSVNSSA | ASMILGAVTV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NRPDFVIQRW | QWFLLAVAIQ | CFNCVLACLP | TRIISRINGV | ATYLNTAFLF | IAGITILAYG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GKNHNFVKGT | KIWGDYINTT | QWPTGFAILL | SFNSPIWTMS | GYDAPFHLSE | ECSNASVNAP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KAIVMTAVIG | GVVGWIMQII | VAYTLTDIDS | VMNTSGSMWT | AYLVQAMPPK | AALGILSLTI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ISAIIMGQSA | LIASSRIAYS | YARDGILPFS | GWIGTVNPYT | QTPVNAVICN | CIISILILFL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TFAGTVTLDA | VFSVGAVAAF | IAFTVPIAIR | VFFTKDADFR | RGPWNLGKFS | RPIGLLAVSF |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VALMIPILCF | PSVKNPTAQE | MNWTCLVYGG | PMLFTLVWYA | ISARKWFKGP | KASAHYKRPG |
| 550 | 560 | ||||
| EESSDIVEGV | QADIPSSSDQ | LKIKGDL |